2. Anti-infection
  3. Bacterial
  4. Glenthmycin E

Glenthmycin E is an antibacterial agent found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin E inhibits growth of multiple bacterial and exhibits no detectable cytotoxicity to eukaryotic cells including fungal and human carcinoma cells. Glenthmycin E can be used for the research of bacterial infections.

For research use only. We do not sell to patients.

Glenthmycin E

Glenthmycin E Chemical Structure

CAS No. : 3040055-84-0

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Glenthmycin E:

Glenthmycin E Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Glenthmycin E is an antibacterial agent found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin E inhibits growth of multiple bacterial and exhibits no detectable cytotoxicity to eukaryotic cells including fungal and human carcinoma cells. Glenthmycin E can be used for the research of bacterial infections[1].

In Vitro

Glenthmycin E (0.01-30 μM; 16-24 h) inhibits the growth of Staphylococcus aureus ATCC 25923 (IC50 = 4.9 μM), Enterococcus faecalis (IC50 = 6.2 μM), methicillin-resistant S. aureus ATCC 43300 (IC50 = 3.9 μM), methicillin-resistant S. aureus ATCC 33591 (IC50 = 2.3 μM), and vancomycin-resistant Enterococci (IC50 = 3.2 μM)[1].
Glenthmycin E (48 h) does not exhibit significant cytotoxicity against SW620 or NCI-H460 human carcinoma cells (IC50 >30 μM), nor does it inhibit growth of Candida albicans, Escherichia coli, Mycobacterium bovis BCG, or Mycobacterium tuberculosis H37Ra at concentrations up to 30 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Glenthmycin E Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: human colorectal carcinoma (SW620), human lung carcinoma (NCI-H460) cells
Concentration: 10 nM-30 μM
Incubation Time: 48 h
Result: Exhibited no significant cytotoxicity against SW620 or NCI-H460 cells (IC50 >30 μM).
Molecular Weight

889.03

Formula

C50H64O14
CAS No.
SMILES

C[C@@]12[C@@]3(C[C@H](C(C(O)=O)=C2)C)C(O)=C(C([C@]4([C@@]5([H])[C@@](C=C([C@@]4([H])/C(C)=C/CC/C(C)=C/1)C)([H])[C@H](CC[C@@H]5C)O[C@H]6[C@@H]([C@@H]([C@@H]([C@H](O6)C)OC(C7=C(C=C(C=C7C)OC)OC)=O)O)O)C)=O)C(O3)=O
Structure Classification
Initial Source

Streptomyces sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Glenthmycin E Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glenthmycin E3040055-84-0BacterialCandida albicansmethicillin-resistant S. aureus ATCC 43300SW620methicillin-resistant S. aureus ATCC 33591Staphylococcus aureus ATCC 25923NCI-H460methicillin-resistant Staphylococcus aureusEnterococcus faecalisStreptomyces sp. CMB-PB041vancomycin-resistant EnterococciInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Glenthmycin E
Cat. No.:
HY-N19290
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.