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Results for "

DT

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) Bcl-2 Family (2) c-Fms (1) Complement System (3) Dengue virus (1) DNA/RNA Synthesis (7) E3 Ligase Ligand-Linker Conjugates (1) Flavivirus (1) Fluorescent Dye (1) Guanylate Cyclase (1) HCV (2) Integrin (1) Isotope-Labeled Compounds (2) Ligands for Target Protein for PROTAC (1) MicroRNA (2) Nucleoside Antimetabolite/Analog (2) Parasite (1) Phosphatase (3) PROTACs (1) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (3) TGF-beta/Smad (1) Transthyretin (TTR) (1) VEGFR (1)
By Research Areas:	Cancer (10) Cardiovascular Disease (3) Infection (5) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (2)

By Targets:

Apoptosis (1)

Bacterial (1)

Bcl-2 Family (2)

c-Fms (1)

Complement System (3)

Dengue virus (1)

DNA/RNA Synthesis (7)

E3 Ligase Ligand-Linker Conjugates (1)

Flavivirus (1)

Fluorescent Dye (1)

Guanylate Cyclase (1)

HCV (2)

Integrin (1)

Isotope-Labeled Compounds (2)

Ligands for Target Protein for PROTAC (1)

MicroRNA (2)

Nucleoside Antimetabolite/Analog (2)

Parasite (1)

Phosphatase (3)

PROTACs (1)

Ser/Thr Protease (1)

Small Interfering RNA (siRNA) (3)

TGF-beta/Smad (1)

Transthyretin (TTR) (1)

VEGFR (1)

By Research Areas:

Cancer (10)

Cardiovascular Disease (3)

Infection (5)

Inflammation/Immunology (4)

Metabolic Disease (1)

Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112929

DT-061 Maximum Cited Publications 10 Publications Verification	Phosphatase	Cancer
DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis .

HY-130604

DT2216 1 Publications Verification	Bcl-2 Family PROTACs Apoptosis	Cancer
DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets. DT2216 is composed of the Bcl-2 family protein inhibitor Navitoclax (HY-10087), a linker, and a VHL E3 ubiquitin ligase (Red: Navitoclax; Blue: VHL ligand; Black: linker) .

HY-120272

SMAP-2

DT-1154
Phosphatase Cancer

SMAP-2 (DT-1154) is an orally active protein phosphatase 2A (PP2A) activator, with anti-cancer activity .

SMAP-2 DT-1154	Phosphatase	Cancer
SMAP-2 (DT-1154) is an orally active protein phosphatase 2A (PP2A) activator, with anti-cancer activity .

HY-156512

DT-6	TGF-beta/Smad	Cancer
DT-6 is an effective TGF-β1 inhibitor. DT-6 inhibits M2 macrophage induced epithelial to mesenchymal transition and invasive migration of cancer cells. DT-6 can be used for cancer diseases research .

HY-P0142

DT-3	Guanylate Cyclase	Inflammation/Immunology
DT-3 is a membrane-permeable protein kinase G Iα inhibitory peptide. DT-3 is a guanylyl cyclase? inhibitor and shows pharmacological blockade of the cGMP–PKG signalling .

HY-A0152A

D-Thyroxine sodium D-T4 sodium	Others	Cardiovascular Disease
D-thyroxine (D-T4) sodium is a laevorotatory isomer of thyroxine, and can used for the research of the dysfunctions of thyroid .

HY-A0152

D-Thyroxine

D-T4

D-Thyroxine (D-T4) is a thyroid hormone that can inhibit TSH secretion. D-Thyroxine can be used for the research of hypercholesterolemia .

D-Thyroxine D-T4
D-Thyroxine (D-T4) is a thyroid hormone that can inhibit TSH secretion. D-Thyroxine can be used for the research of hypercholesterolemia .

HY-W013068S3

DMT-dT Phosphoramidite-d11	Isotope-Labeled Compounds DNA/RNA Synthesis	Others
DMT-dT Phosphoramidite-d₁₁ is deuterium labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

HY-W013068S2

DMT-dT Phosphoramidite-13C	Isotope-Labeled Compounds DNA/RNA Synthesis	Others
DMT-dT Phosphoramidite- ¹³C is ¹³C-labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

HY-W013068S1

DMT-dT Phosphoramidite-15N2	DNA/RNA Synthesis	Others
DMT-dT Phosphoramidite- ¹⁵N₂ is the ¹⁵N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].

HY-W013068

DMT-dT Phosphoramidite

DNA/RNA Synthesis Others

DMT-dT Phosphoramidite is typically used in the synthesis of DNA .

DMT-dT Phosphoramidite	DNA/RNA Synthesis	Others
DMT-dT Phosphoramidite is typically used in the synthesis of DNA .

HY-112929B

(1S,2S,3R)-DT-061 1 Publications Verification	Phosphatase	Cancer
(1S,2S,3R)-DT-061 is an enantiomer of DT-061 (HY-112929). DT-061 is an orally active activator of protein phosphatase 2A (PP2A). (1S,2S,3R)-DT-061 can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis .

HY-138597

5'-O-TBDMS-dT

DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer

5'-O-TBDMS-dT is a nucleoside with protective and modification effects.

5'-O-TBDMS-dT	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
5'-O-TBDMS-dT is a nucleoside with protective and modification effects.

HY-D1901

FAM-dT phosphoramidite	Fluorescent Dye	Others
FAM-dT phosphoramidite (Compound 21) is a fully protected labelled nucleoside phosphoramidite that can be incorporated into oligonucleotides .

HY-W013068S

DMT-dT Phosphoramidite-13C10,15N2	DNA/RNA Synthesis	Others
DMT-dT Phosphoramidite- ¹³C₁₀, ¹⁵N₂ is the ¹³C and ¹⁵N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].

HY-20140

5'-O-DMT-dT 5'-O-(4,4'-Dimethoxytrityl)thymidine	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides .

HY-132609

Patisiran sodium	Small Interfering RNA (siRNA) Transthyretin (TTR)	Neurological Disease
Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis .

HY-132598

Miravirsen SPC-3649	MicroRNA HCV	Infection Inflammation/Immunology
Miravirsen (SPC-3649) is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen inhibits HCV replication. Miravirsen can be used in research of HCV infection .

HY-147079

Egaptivon pegol ARC 1779	Integrin	Cardiovascular Disease
Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy.

HY-132600

RG-101 Temavirsen	MicroRNA HCV	Infection
RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication .

HY-145720

Cemdisiran ALN-CC5	Small Interfering RNA (siRNA) Complement System	Others
Cemdisiran is an N-acetylgalactosamine (GalNAc) conjugated siRNA for the research of complement-mediated diseases by suppressing liver production of complement 5 (C5) protein.

HY-44432

Navitoclax-piperazine ABT-263-piperazine	Bcl-2 Family Ligands for Target Protein for PROTAC	Cancer
Navitoclax-piperazine (ABT-263-piperazine) is a B-cell lymphoma extra large (BCL-XL) inhibitor. Navitoclax-piperazine and a VHL ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC DT2216 (HY-130604) .

HY-132581

Tadnersen BIIB078; IONIS-C9Rx	Others	Neurological Disease
Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets *C9ORF72* transcript variants 1 and 3 that carry the expansion .

HY-130849

(S,R,S)-AHPC-Me-C5-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604) .

HY-109561

Pegaptanib sodium EYE001; NX1838	VEGFR	Metabolic Disease Inflammation/Immunology
Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .

HY-132591

Inclisiran ALN-PCSsc	Small Interfering RNA (siRNA) Ser/Thr Protease	Cardiovascular Disease
Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research .

HY-P99245

Emactuzumab RG 7155; RO 5509554	c-Fms	Cancer
Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with K_i value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

HY-147080

Avacincaptad pegol sodium ARC1905	Complement System	Others
Avacincaptad pegol (ARC1905) is an anti-C5 RNA aptamer that inhibits the cleavage of complement factor 5 (C5) into C5a and C5b. Avacincaptad pegol is being used for the study of age-related macular degeneration (AMD).

HY-148457

Avacincaptad pegol	Complement System	Infection Inflammation/Immunology
Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA) .

HY-124801

ABMA	Flavivirus Dengue virus Bacterial Parasite	Infection
ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity .

Cat. No.	Product Name	Type

HY-W013068

DMT-dT Phosphoramidite

Gene Sequencing and Synthesis

DMT-dT Phosphoramidite is typically used in the synthesis of DNA .

DMT-dT Phosphoramidite	Gene Sequencing and Synthesis
DMT-dT Phosphoramidite is typically used in the synthesis of DNA .

Cat. No.	Product Name	Target	Research Area

HY-P2692A

DT-2

Peptides Cancer

DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG). DT-2 inhibits PKG catalyzed phosphorylation (K_{i_{: 12.5 nM) .}}

DT-2	Peptides	Cancer
DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG). DT-2 inhibits PKG catalyzed phosphorylation (K_{i_{: 12.5 nM) .}}

HY-P0142

DT-3	Guanylate Cyclase	Inflammation/Immunology
DT-3 is a membrane-permeable protein kinase G Iα inhibitory peptide. DT-3 is a guanylyl cyclase? inhibitor and shows pharmacological blockade of the cGMP–PKG signalling .

Cat. No.	Product Name

HY-K0228

Oligo (dT)₃₀ Magnetic Beads
Oligo (dT)₃₀ Magnetic Beads are designed for the rapid isolation of highly purified, intact mRNA from eukaryotic total RNA or directly from crude extracts of cells, plant and animal tissues.

Cat. No.	Product Name	Target	Research Area

HY-P99245

Emactuzumab RG 7155; RO 5509554	c-Fms	Cancer
Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with K_i value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

Species:	Human (3) Mouse (2)
Tag:	SUMO (2) His (5)
Source:	HEK293 (1) P. pastoris (2) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72487

	HB-EGF Protein, Human (HEK293, His) Proheparin-binding EGF-like growth factor; HB-EGF; DT-R; DTS; HEGFL	Human	HEK293
	HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (HEK293, His) is the recombinant human-derived HB-EGF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of HB-EGF Protein, Human (HEK293, His) is 129 a.a., with molecular weight of ~18 kDa.

HY-P72168

	DCT Protein, Human (His-SUMO) L dopachrome tautomerase; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Delta isomerase; L-dopachrome Delta-isomerase; L-dopachrome tautomerase; TRP 2; TRP-2; TRP2; Tyrosinase related protein 2; Tyrosinase-related protein 2; TYRP2; TYRP2_HUMAN	Human	E. coli
	DCT Protein is essential in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a pivotal step in melanin synthesis. DCT Protein, Human (His-SUMO) is the recombinant human-derived DCT protein, expressed by E. coli , with N-SUMO, N-10*His labeled tag. The total length of DCT Protein, Human (His-SUMO) is 449 a.a., with molecular weight of ~71.3 kDa.

HY-P72169

	DCT Protein, Mouse (His-SUMO) Dct; Tyrp-2; Tyrp2; L-dopachrome tautomerase; DCT; DT; EC 5.3.3.12; DOPAchrome conversion factor; DOPAchrome isomerase; DOPAchrome oxidoreductase; L-dopachrome Delta-isomerase; SLATY locus protein; Tyrosinase-related protein 2; TRP-2; TRP2	Mouse	E. coli
	DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of DCT Protein, Mouse (His-SUMO) is 449 a.a., with molecular weight of ~69.7 kDa.

HY-P71840

	DST Protein, Human (P.pastoris, His) DST; BPAG1; DMH; DT; Dystonia musculorum protein; Hemidesmosomal plaque protein	Human	P. pastoris
	DST proteins integrate intermediate filaments, actin, and microtubule networks. DST Protein, Human (P.pastoris, His) is the recombinant human-derived DST protein, expressed by P. pastoris , with N-His labeled tag. The total length of DST Protein, Human (P.pastoris, His) is 195 a.a., with molecular weight of ~23.7 kDa.

HY-P71831

	Azoreductase/NQO1 Protein, Mouse (P.pastoris, His) Nqo1; Dia4; Nmo1; Nmor1; NAD(P)H dehydrogenase [quinone] 1; EC 1.6.5.2; Azoreductase; DT-diaphorase; DTD; Phylloquinone reductase; Quinone reductase 1; QR1	Mouse	P. pastoris
	The azoreductase/NQO1 protein reduces quinones to hydroquinone using NADH or NADPH as an electron donor. Azoreductase/NQO1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Azoreductase/NQO1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Azoreductase/NQO1 Protein, Mouse (P.pastoris, His) is 273 a.a., with molecular weight of ~33 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P81505

TRP2 Antibody (YA1250)

TRP-2; TRP2; TYRP2; DCT; DT
IHC-P Human

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