(S,R,S)-AHPC-Me-C5-COOH
Based on 1 Customer Validation
(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604).
For research use only. We do not sell to patients.
- Purity: 96.87%
- CAS No.: 2229976-21-8
- Formula: C30H42N4O6S
- Molecular Weight:586.74
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
|
VHL |
Chemical Information
-
CAS No. 2229976-21-8
-
Appearance Solid
-
Molecular Weight 586.74
-
Formula C30H42N4O6S
-
Color Off-white to light yellow
-
SMILES
O=C(N[C@H](C1=CC=C(C2=C(C)N=CS2)C=C1)C)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCC(O)=O)=O)=O)C[C@H](O)C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (170.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (275 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7043 mL | 8.5217 mL | 17.0433 mL | 42.6083 mL |
| 5 mM | 0.3409 mL | 1.7043 mL | 3.4087 mL | 8.5217 mL | |
| 10 mM | 0.1704 mL | 0.8522 mL | 1.7043 mL | 4.2608 mL | |
| 15 mM | 0.1136 mL | 0.5681 mL | 1.1362 mL | 2.8406 mL | |
| 20 mM | 0.0852 mL | 0.4261 mL | 0.8522 mL | 2.1304 mL | |
| 25 mM | 0.0682 mL | 0.3409 mL | 0.6817 mL | 1.7043 mL | |
| 30 mM | 0.0568 mL | 0.2841 mL | 0.5681 mL | 1.4203 mL | |
| 40 mM | 0.0426 mL | 0.2130 mL | 0.4261 mL | 1.0652 mL | |
| 50 mM | 0.0341 mL | 0.1704 mL | 0.3409 mL | 0.8522 mL | |
| 60 mM | 0.0284 mL | 0.1420 mL | 0.2841 mL | 0.7101 mL | |
| 80 mM | 0.0213 mL | 0.1065 mL | 0.2130 mL | 0.5326 mL | |
| 100 mM | 0.0170 mL | 0.0852 mL | 0.1704 mL | 0.4261 mL |