1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-Me-C5-COOH

(S,R,S)-AHPC-Me-C5-COOH 

Cat. No.: HY-130849
Handling Instructions

(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604).

For research use only. We do not sell to patients.

(S,R,S)-AHPC-Me-C5-COOH Chemical Structure

(S,R,S)-AHPC-Me-C5-COOH Chemical Structure

CAS No. : 2229976-21-8

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Description

(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].

IC50 & Target[1]

VHL

 

In Vitro

DT2216 is a selective B-cell lymphoma extra large (BCL-XL) PROTAC degrader[1].

Molecular Weight

586.74

Formula

C₃₀H₄₂N₄O₆S

CAS No.

2229976-21-8

SMILES

O=C(N[[email protected]](C1=CC=C(C2=C(C)N=CS2)C=C1)C)[[email protected]]3N(C([[email protected]](C(C)(C)C)NC(CCCCCC(O)=O)=O)=O)C[[email protected]](O)C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

(S,R,S)-AHPC-Me-C5-COOHE3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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(S,R,S)-AHPC-Me-C5-COOH
Cat. No.:
HY-130849
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