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Emactuzumab

(Synonyms: RG 7155; RO 5509554)
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Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with Ki value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

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  • Pureté: 97.60%
  • CAS No.: 1448221-67-7
  • Masse moléculaire:144.41 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Emactuzumab
  • Experimental Validation Results for Emactuzumab
  • Experimental Validation Results for Emactuzumab
  • Emactuzumab Chemical Structure
    Emactuzumab Chemical Structure
CAS No.: 1448221-67-7
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Emactuzumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CSF1R Protein, Human (HEK293, HY-P72948) can bind Emactuzumab. The EC50 for this effect is 8.427 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 THP-1 cells with Emactuzumab (HY-P99245, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Emactuzumab Chemical Structure
    1/16
  • Emactuzumab
  • Immobilized CSF1R Protein, Human (HEK293, HY-P72948) can bind Emactuzumab. The EC50 for this effect is 8.427 ng/mL.
  • Flow cytometric analysis of 1.5X106 THP-1 cells with Emactuzumab (HY-P99245, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).