58 Results for "

NRP-1

" in MedChemExpress (MCE) Product Catalog:
Products (58)

58 Results for "NRP-1" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-10799
CAS No.: 1210945-69-9
Purity:  98.03%
Target:  

Complement System

Research Areas:  

Cancer

EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2 [1].
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5
5 Cited Publications
Cat. No.: HY-112151
CAS No.: 2227996-00-9
Target:  

Complement System

Research Areas:  

Cancer

EG01377 is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1. EG01377 has antiangiogenic, antimigratory, and antitumor effects [1].
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5
5 Cited Publications
Cat. No.: HY-112151A
CAS No.: 2749438-61-5
Purity:  98.98%
Target:  

Complement System

Research Areas:  

Cancer

EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects [1].
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3
3 Cited Publications
Cat. No.: HY-P70147
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NRP1; Transmembrane Receptor; Neuropilin 1; CD304 Antigen; VEGF165R; DKFZp686M1967; NRP; Neuropilin; Neuropilin-1; BDCA4; CD304; NP1; Vascular Endothelial Cell Growth Factor 165 Receptor
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P1663A
ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1, used in the research of angiogenesis [1]. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .
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Cat. No.: HY-P99386
CAS No.: 1205533-60-3
Synonyms: MNRP-1685A

Research Areas:  

Cancer

Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer [1] .
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Cat. No.: HY-P3448
CAS No.: 2580154-02-3
Synonyms: CEND-1; iRGD; LSTA1
Research Areas:  

Cancer

Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors [1] .
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Cat. No.: HY-P10787
CAS No.: 1354801-55-0
Target:  

Complement System

Research Areas:  

Cancer

tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. tLyP-1 peptide specifically binds to NRP-1 to target tumor cells [1].
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Cat. No.: HY-133034
CAS No.: 2569598-01-0
Purity:  99.71%
Target:  

Complement System

Research Areas:  

Cancer

NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research [1].
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Cat. No.: HY-P10097
CAS No.: 329189-44-8
Target:  

VEGFR

Research Areas:  

Others

Flt2-11 is a anti-angiogenic peptide, and specifically binds NRP-1. Flt2-11 inhibits NRP-1/sVEGFR-1 interaction.
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Cat. No.: HY-RS09579
Research Areas:  

Others

NRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16529
Research Areas:  

Others

Nrp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nrp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P0122B
Target:  

Peptides

Research Areas:  

Cancer

iRGD peptide 1 TFA is the prototypic tumor-specific tissue-penetrating peptide, which delivers agents deep into extravascular tumor tissue. iRGD peptide 1 TFA has anti-metastatic activity [1].
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Cat. No.: HY-P11286
CAS No.: 632358-46-4
Target:  

Complement System

Research Areas:  

Cancer

A7RC is a multifunctional peptide used in tumor-targeted therapy, with Cysteine added to the C-terminal of the A7R peptide (sequence: ATWLPPR). A7R (HY-P1663) is a ligand of the NRP-1 receptor, regulating intracellular signal transduction related to tumor vascularization and tumor growth [1].
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Cat. No.: HY-147762
CAS No.: 483289-96-9
Purity:  99.05%
Target:  

Complement System

Research Areas:  

Cancer

NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist [1].
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Cat. No.: HY-P3449
CAS No.: 2522933-44-2
Synonyms: TRS01
Dazdotuftide (TRS01) is a multi-target immunomodulator composed of tuftsin and phosphorylcholine-related groups. Dazdotuftide regulates TLR4/NF-κB and NRP1/VEGF165 related signaling pathways and inhibits the production of pro-inflammatory cytokines. Dazdotuftide can be used in studies related to inflammation and immunoregulation [1] .
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Cat. No.: HY-163062
CAS No.: 2983719-82-8
Research Areas:  

Cancer

Tubulin/NRP1-IN-1 (compound TN-2) is a dual inhibitor of Tubulin and NRP1 with IC50s of 0.71 and 0.85 μM, respectively. Tubulin/NRP1-IN-1 significantly inhibits the viability of prostate tumor cell lines and induces apoptosis [1].
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Cat. No.: HY-P3448S
Synonyms: CEND-1-13C6,15N2; iRGD-13C6,15N2; LSTA1-13C6,15N2
Certepetide- 13C6, 15N2 (CEND-1- 13C6, 15N2) is the 13C- and 15N-labeled Certepetide (HY-P3448). Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors [1] .
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Cat. No.: HY-128446
CAS No.: 1210360-87-4
Target:  

VEGFR

Research Areas:  

Neurological Disease

CAY10781 (Compound 11) is an inhibitor of the neuropilin-1 (NRP-1) and VEGF-A interaction. CAY10781 inhibits VEGF-A-induced phosphorylation of VEGFR2 in Catecholamine A-differentiated (CAD) cells [1]< sup>.
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Cat. No.: HY-RS22960
Research Areas:  

Others

Nrp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nrp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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