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NSC 11228

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By Targets:	ACSL Family (1) Amyloid-β (3) Androgen Receptor (1) Apoptosis (6) Arf Family GTPase (1) Autophagy (6) Bacterial (2) Biochemical Assay Reagents (2) BMX Kinase (1) c-Met/HGFR (3) CXCR (1) Drug Derivative (2) Epigenetic Reader Domain (1) IRE1 (6) MicroRNA (12) Mitophagy (6) Parasite (1) PDGFR (6) Reference Standards (2) Trk Receptor (1) VEGFR (6) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (2) Endocrinology (1) Infection (4) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (3)
Oligonucleotides:	miRNA mimics (3) miRNA agomirs (3) miRNA antagomirs (3) MicroRNAs (12) miRNA inhibitors (3)

Inhibitors & Agonists

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10255A

Sunitinib Maximum Cited Publications 92 Publications Verification SU 11248	VEGFR PDGFR IRE1 Mitophagy Autophagy Apoptosis	Cancer
Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

HY-N6707

Triacsin C 5+ Cited Publications WS 1228A; FR 900190	ACSL Family Parasite	Infection Cardiovascular Disease
Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .

HY-10255

Sunitinib Malate Maximum Cited Publications 92 Publications Verification SU 11248 Malate	PDGFR VEGFR IRE1 Mitophagy Autophagy Apoptosis	Infection Inflammation/Immunology Cancer
Sunitinib (SU 11248) Malat is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib Malat, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

HY-117669

VPC-14228	Androgen Receptor	Cancer
VPC-14228 is an inhibitor that selectively targets androgen receptor DNA binding domain (AR-DBD). VPC-14228 inhibits the interaction between AR and DNA, thereby blocking AR-mediated transcriptional activation. VPC-14228 does not rely on nuclear localization inhibition, but rather inhibits the activity of full-length AR and splice variant AR-V7 by interfering with AR binding to chromatin. And VPC-14228 has high selectivity for other nuclear receptors such as ER and PR. VPC-14228 can be used in the study of prostate cancer [2].

HY-110269

VUF 11222	CXCR	Inflammation/Immunology
VUF 11222 (Compound 38) is a CXCR3 non-peptide-like agonist. VUF 11222 can be used in the study of inflammation .

HY-10255R

Sunitinib Malate (Standard) SU 11248 Malate (Standard)	Reference Standards PDGFR VEGFR IRE1 Mitophagy Autophagy Apoptosis	Cancer
Sunitinib (Malate) (Standard) is the analytical standard of Sunitinib (Malate). This product is intended for research and analytical applications. Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

HY-R00104

*hsa-miR-12128* mimic**	MicroRNA	Cancer
hsa-miR-12128 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-12128 mimic hsa-miR-12128 mimic

HY-R00121

*hsa-miR-1228-3p mimic*	MicroRNA	Cancer
hsa-miR-1228-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-1228-3p mimic hsa-miR-1228-3p mimic

HY-10255AS

Sunitinib-d10 SU 11248-d₁₀	VEGFR PDGFR IRE1 Mitophagy Autophagy Apoptosis	Cancer
Sunitinib-d₁₀ (SU 11248-d₁₀) is a deuterium labeled Sunitinib. Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

HY-179396

*T-1228*	Bacterial	Infection
T-1228 is a highly selective LpxC inhibitor. T-1228 can effectively block the synthesis of LPS (HY-D1056), causing defects in the bacterial outer membrane structure, increasing membrane permeability, and ultimately leading to bacterial cell death. T-1228 can be used for the study of Gram-negative bacterial infections .

HY-U00147

Nicotinoyl cyclandelate RV 12128	Biochemical Assay Reagents	Cardiovascular Disease
Nicotinoyl cyclandelate can be used to lower the perfusion pressure of cerebral blood vessels and the blood pressure of femoral artery.

HY-10255C

Sunitinib glucuronate Maximum Cited Publications 92 Publications Verification SU 11248 glucuronate	PDGFR VEGFR IRE1 Mitophagy Autophagy Apoptosis	Cancer
Sunitinib (SU 11248) glucuronate is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib glucuronate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

HY-10255AR

Sunitinib (Standard) SU 11248 (Standard)	Reference Standards VEGFR PDGFR IRE1 Mitophagy Autophagy Apoptosis	Cancer
Sunitinib (Standard) is the analytical standard of Sunitinib. This product is intended for research and analytical applications. Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

HY-P1051

*β-Amyloid (12-28)* Amyloid β-Protein (12-28)	Amyloid-β	Neurological Disease
β-Amyloid (12-28) (Amyloid β-Protein (12-28)) is a peptide fragment of β-amyloid protein (β1-42). β1-42, a 42 amino acid protein , is the major component of senile plaque cores. β-Amyloid (12-28) shows aggregation properties. β-Amyloid (12-28) has the potential for Alzheimer’s disease research .

HY-157148

*1D228*	c-Met/HGFR Trk Receptor	Cancer
1D228 is a c-Met/TRK inhibitor with antitumor activity. 1D228 inhibits cyclin D1 to induce G0/G1 arrest and inhibit cancer cell proliferation and migration. 1D228 can be used in the study of gastric, liver and vascular tumors .

HY-156860

WP 1122	Drug Derivative	Cancer
WP 1122 is a 2-deoxy-D-glucose (HY-13966) analog that is a potent cytotoxic agent. WP 1122 is a glycolysis inhibitor. WP 1122 can be used for the research of cancer .

HY-133180

YW1128	Wnt β-catenin	Metabolic Disease
YW1128 (compound 3a) is a potent Wnt/β-Catenin inhibitor. YW1128 induces the proteasome degradation of β-catenin and subsequent inhibits the Wnt/β-catenin signaling in cells. YW1128 significantly decreases hepatic lipid accumulation. YW1128 improves glucose tolerance of high fat diet-fed mice without noticeable toxicity. YW1128 down regulates the genes involved in the glucose and fatty acid anabolism .

HY-177144

CDD-1128	Epigenetic Reader Domain	Endocrinology
CDD-1128 (Compound 11) is a potent inhibitor of BRDT-BD2. CDD-1128 has an IC₅₀ of 521 nM against BRDT-BD2. CDD-1128 can be studied in research on nonhormonal contraceptive agent .

HY-149628

HM-1228	Biochemical Assay Reagents	Others
HM-1228 is a corrosion inhibitor for carbon-steel in oilfield produced water .

HY-P1893

*β-Amyloid (11-22)*	Amyloid-β	Neurological Disease
β-Amyloid (11-22) is a peptide fragment of β-Amyloid.

HY-173280

Brefeldin A 4-O-nicotinate CHNQD-01228	Arf Family GTPase BMX Kinase	Cancer
Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins. The IC₅₀ value for the proliferation of T24 cells is 0.22 μM. It can also dose-dependently inhibit the migration and colony formation of T24 cells, induce G1 phase arrest and trigger Apoptosis. Brefeldin A 4-O-nicotinate exerts its anti-cancer activity by targeting the BMX protein to inhibit the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, as well as by inhibiting the Arf1 protein to eliminate bladder cancer stem cells and activate anti-tumor immunity. Brefeldin A 4-O-nicotinate can be used in the research related to bladder cancer .

HY-RI00121

*hsa-miR-1228-3p inhibitor*	MicroRNA	Cancer
hsa-miR-1228-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-1228-3p inhibitor hsa-miR-1228-3p inhibitor

HY-RI00121A

*hsa-miR-1228-3p antagomir*	MicroRNA	Cancer
hsa-miR-1228-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1228-3p antagomir hsa-miR-1228-3p antagomir

HY-R00122

*hsa-miR-1228-5p mimic*	MicroRNA	Cancer
hsa-miR-1228-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-1228-5p mimic hsa-miR-1228-5p mimic

HY-P1051A

*β-Amyloid (12-28) TFA* Amyloid β-Protein (12-28) TFA; Amyloid Beta-Peptide (12-28) (human) TFA; β-Amyloid protein fragment(12-28) TFA	Amyloid-β	Neurological Disease
β-Amyloid (12-28) (TFA) (Amyloid β-Protein (12-28) (TFA)) is a peptide fragment of β-amyloid protein (β1-42). β1-42, a 42 amino acid protein , is the major component of senile plaque cores. β-Amyloid (12-28) (TFA) shows aggregation properties. β-Amyloid (12-28) (TFA) has the potential for Alzheimer’s disease research .

HY-E70749

MET D1228N Recombinant Human Active Protein Kinase	c-Met/HGFR	Cancer
Mesenchymal-to-epithelial transition (MET) is a receptor tyrosine kinase for hepatocyte growth factor (HGF). MET overactivation is strongly associated with angiogenesis, cellular motility, growth, and invasion. Aberrant MET signaling can drive tumorigenesis in several cancer types through various molecular mechanisms, including MET amplification, MET exon 14 skipping mutation, MET overexpression, and MET fusions. MET D1228N is a mutant of MET. MET D1228N Recombinant Human Active Protein Kinase is a recombinant MET D1228N protein that can be used to study MET D1228N-related functions .

HY-E70748

MET D1228H Recombinant Human Active Protein Kinase	c-Met/HGFR	Cancer
Mesenchymal-to-epithelial transition (MET) is a receptor tyrosine kinase for hepatocyte growth factor (HGF). MET overactivation is strongly associated with angiogenesis, cellular motility, growth, and invasion. Aberrant MET signaling can drive tumorigenesis in several cancer types through various molecular mechanisms, including MET amplification, MET exon 14 skipping mutation, MET overexpression, and MET fusions. MET D1228H is a mutant of MET. MET D1228H Recombinant Human Active Protein Kinase is a recombinant MET D1228H protein that can be used to study MET D1228H-related functions .

HY-106304

ME-1228	Bacterial Drug Derivative	Infection
ME-1228 is an antibacterial agent and sulfur-containing analogue of OCP 9-176. ME 1228 is generally twofold more active than OCP 9-176 against Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Providencia stuartii, Proteus vulgaris, and Serratia marcescens. ME-1228 has antibacterial activity against E. coli UB 1005, P. aeruginosa K779K, and P. aeruginosa E4, with MICs of 0.25, 0.25, and 1 μg/mL, respectively .

HY-RI00104A

*hsa-miR-12128* antagomir**	MicroRNA	Cancer
hsa-miR-12128 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-12128 antagomir hsa-miR-12128 antagomir

HY-R00104A

*hsa-miR-12128* agomir**	MicroRNA	Cancer
hsa-miR-12128 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-12128 agomir hsa-miR-12128 agomir

HY-RI00104

*hsa-miR-12128* inhibitor**	MicroRNA	Cancer
hsa-miR-12128 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-12128 inhibitor hsa-miR-12128 inhibitor

HY-RI00122A

*hsa-miR-1228-5p antagomir*	MicroRNA	Cancer
hsa-miR-1228-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1228-5p antagomir hsa-miR-1228-5p antagomir

HY-R00121A

*hsa-miR-1228-3p agomir*	MicroRNA	Cancer
hsa-miR-1228-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1228-3p agomir hsa-miR-1228-3p agomir

HY-RI00122

*hsa-miR-1228-5p inhibitor*	MicroRNA	Cancer
hsa-miR-1228-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-1228-5p inhibitor hsa-miR-1228-5p inhibitor

HY-R00122A

*hsa-miR-1228-5p agomir*	MicroRNA	Cancer
hsa-miR-1228-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1228-5p agomir hsa-miR-1228-5p agomir

Cat. No.	Product Name	Target	Research Area

HY-P1051

*β-Amyloid (12-28)* Amyloid β-Protein (12-28)	Amyloid-β	Neurological Disease
β-Amyloid (12-28) (Amyloid β-Protein (12-28)) is a peptide fragment of β-amyloid protein (β1-42). β1-42, a 42 amino acid protein , is the major component of senile plaque cores. β-Amyloid (12-28) shows aggregation properties. β-Amyloid (12-28) has the potential for Alzheimer’s disease research .

HY-P1893

*β-Amyloid (11-22)*	Amyloid-β	Neurological Disease
β-Amyloid (11-22) is a peptide fragment of β-Amyloid.

HY-P1051A

*β-Amyloid (12-28) TFA* Amyloid β-Protein (12-28) TFA; Amyloid Beta-Peptide (12-28) (human) TFA; β-Amyloid protein fragment(12-28) TFA	Amyloid-β	Neurological Disease
β-Amyloid (12-28) (TFA) (Amyloid β-Protein (12-28) (TFA)) is a peptide fragment of β-amyloid protein (β1-42). β1-42, a 42 amino acid protein , is the major component of senile plaque cores. β-Amyloid (12-28) (TFA) shows aggregation properties. β-Amyloid (12-28) (TFA) has the potential for Alzheimer’s disease research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6707

Triacsin C 5+ Cited Publications WS 1228A; FR 900190	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	ACSL Family Parasite
Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .

Species:	Human (6) Rhesus Macaque (2) Cynomolgus (2)
Tag:	His (8) Strep (1) GST (6) Fc (1)
Source:	HEK293 (2) sf9 insect cells (5) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700892

	LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, His) LIB; LRRC15; EGM_11224	Rhesus Macaque;Cynomolgus	HEK293
	LRRC15 is a cell membrane-expressed protein belonging to the LRR superfamily. Involved in cell-cell and cell-ECM interactions. The LRRC15 protein regulates the infectivity of SARS-CoV-2 by interacting with its spike protein. LRRC15 activates the β1-integrin /FAK signaling pathway to promote ovarian cancer metastasis. LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant cynomolgus-derived LRRC15 protein, expressed by HEK293 , with C-His labeled tag.

HY-P704768

	LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, Fc) LIB; LRRC15; EGM_11224	Rhesus Macaque;Cynomolgus	HEK293
	LRRC15 is a cell membrane-expressed protein belonging to the LRR superfamily. Involved in cell-cell and cell-ECM interactions. The LRRC15 protein regulates the infectivity of SARS-CoV-2 by interacting with its spike protein. LRRC15 activates the β1-integrin /FAK signaling pathway to promote ovarian cancer metastasis. LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, Fc) is the recombinant cynomolgus-derived LRRC15 protein, expressed by heterologous system, with C-hFc labeled tag.

HY-P705776

	HGFR Protein, Human (Active, D1228A, sf9, His-GST) MET; AUTS9; HGFR; RCCP2; c-Met	Human	sf9 insect cells

HY-P705777

	HGFR Protein, Human (Active, D1228G, sf9, His-GST) MET; AUTS9; HGFR; RCCP2; c-Met	Human	sf9 insect cells

HY-P705778

	HGFR Protein, Human (Active, D1228H, sf9, His-GST) MET; AUTS9; HGFR; RCCP2; c-Met	Human	sf9 insect cells

HY-P705779

	HGFR Protein, Human (Active, D1228V, sf9, His-GST) MET; AUTS9; HGFR; RCCP2; c-Met	Human	sf9 insect cells

HY-P705780

	HGFR Protein, Human (Active, D1228Y, sf9, His-GST) MET; AUTS9; HGFR; RCCP2; c-Met	Human	sf9 insect cells

HY-P72938A

	HGFR Protein, Human (Active, D1228N, sf9, His-GST) Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET	Human	Sf9 insect cells
	The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (Active, D1228N, sf9, His-GST) is the recombinant human-derived HGFR protein, expressed by Sf9 insect cells , with N-His-GST labeled tag.

HY-P703424

	TSI3 Protein, Pseudomonas aeruginosa (His, Strep) Immune protein Tsi3; Anti-toxin protein Tsi3; tsi3; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	Others	E. coli
	TSI3 Protein, Pseudomonas aeruginosa (His, Strep) is the recombinant TSI3, expressed by E. coli , with Strep, His labeled tag. ,

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Species
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Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-10255AS

Sunitinib-d10
Sunitinib-d₁₀ (SU 11248-d₁₀) is a deuterium labeled Sunitinib. Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor with IC₅₀s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively . Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation .

Host:	Mouse (1) Rabbit (5)
Reactivity:	Human (6) Rat (2) Mouse (2)
Application:	IHC-P (6) ICC/IF (2) IF-Tissue (1) IP (1) IHC-F (1) WB (1) FC (1)
Isotype:	IgG (6)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (3)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81383

	CD79b Antibody (YA1128) CD79B; AGM6; B29; IGB	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	CD79b Antibody (YA1128) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD79b.

HY-P81483

	IL-5 Receptor alpha Antibody (YA1228) IL-5 Receptor alpha; interleukin 5 receptor; alpha; IL5R; CD125; CDw125; HSIL5R3	IHC-P	Human
	IL-5 Receptor alpha Antibody (YA1228) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-5 Receptor alpha.

HY-P81377

	alpha 1 Antitrypsin Antibody (YA1122) SERPINA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1	IHC-P	Human
	alpha 1 Antitrypsin Antibody (YA1122) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1 Antitrypsin.

HY-P81483A

	IL-5 Receptor alpha Antibody (YA1228)(PBS only) IL-5 Receptor alpha; interleukin 5 receptor; alpha; IL5R; CD125; CDw125; HSIL5R3	IHC-P	Human
	IL-5 Receptor alpha Antibody (YA1228) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-5 Receptor alpha.

HY-P81377A

	alpha 1 Antitrypsin Antibody (YA1122)(PBS only) SERPINA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1	IHC-P	Human
	alpha 1 Antitrypsin Antibody (YA1122) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1 Antitrypsin.

HY-P86740

	PTEN Antibody (YA6432) ITGA 2; MGC11227; MHAM; MMAC 1; MMAC1; Bannayan Zonana; BZS a; Multiple hamartoma(Cowden syndrome); Mutated in Mutiple Advanced Cancers 1; Phosphatase and Tensin Homolog; Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN; Phosphatidylinositol 345 trisphosphate 3 phosphatase; Platelet antigen BR; PTEN 1; PTEN1; Tensin homolog; TEP 1; TEP1; VLA 2 Receptor alpha Subunit.	IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Mouse, Rat
	PTEN Antibody (YA6432) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to PTEN.

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Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-R00104

*hsa-miR-12128* mimic**		MicroRNAs miRNA mimics
hsa-miR-12128 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R00121

*hsa-miR-1228-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-1228-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI00121

*hsa-miR-1228-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-1228-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00121A

*hsa-miR-1228-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-1228-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00122

*hsa-miR-1228-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-1228-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI00104A

*hsa-miR-12128* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-12128 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00104A

*hsa-miR-12128* agomir**		MicroRNAs miRNA agomirs
hsa-miR-12128 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00104

*hsa-miR-12128* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-12128 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00122A

*hsa-miR-1228-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-1228-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00121A

*hsa-miR-1228-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-1228-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00122

*hsa-miR-1228-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-1228-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R00122A

*hsa-miR-1228-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-1228-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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