2. Search Result
Search Result
Results for "

anti-HIV-1 agent

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

3

Natural
Products

1

Click Chemistry

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-104012
    Islatravir
    2 Publications Verification

    MK-8591

    		 HIV Reverse Transcriptase Infection Inflammation/Immunology
    Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Islatravir
  • HY-115488A
    BNM-III-170

    		HIV Infection
    BNM-III-170, CD4-mimeticcompound, is an anti-HIV-1 agent. BNM-III-170 binds to the Phe43 cavity of HIV 1 gp120. BNM-III-170 can inhibits HIV-1 viral entry into target cells. BNM-III-170 can be used for the research of HIV-1 infection .
    BNM-III-170
  • HY-N0867
    13-Oxyingenol-13-dodecanoate

    		HIV ULK Bcl-2 Family Infection Cancer
    13-Oxyingenol-dodecanoate (13OD) is a tumor suppressor agent. 13-Oxyingenol-dodecanoate has anti-HIV-1 activity with EC50 value of 33.7 nM .13-Oxyingenol-dodecanoate can induce the expression of ULK1 to effect mitochondrial dysfunction and cellular autophagy. 13-Oxyingenol-dodecanoate also increases the expression of BAX and suppresses the expression of BCL-2 to effect apoptosis .
    13-Oxyingenol-13-dodecanoate
  • HY-N10958
    Wikstrol A

    		Fungal HIV Microtubule/Tubulin Infection
    Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM .
    Wikstrol A
  • HY-10892
    HEPT

    		HIV Infection
    HEPT is a potent and selective anti-HIV-1 agent .
    HEPT
  • HY-118711
    HI-346

    		HIV Reverse Transcriptase Infection
    HI-346 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1 with an IC50 value against the HIV-1 virus strain (HTLV-IIIB) of 3 nM. HI-346 is a vaginal bactericidal contraceptive agent, with its sperm-killing activity having an EC50 value of 42 μM. HI-346 shows no cytotoxicity to normal cells at effective concentrations. HI-346 can be used in anti-HIV-1 and contraceptive research .
    HI-346
  • HY-125810
    4'-Ethynyl-2'-deoxyadenosine

    		HIV Reverse Transcriptase Infection Inflammation/Immunology
    4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity . 4'-Ethynyl-2'-deoxyadenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    4'-Ethynyl-2'-deoxyadenosine
  • HY-116469
    ZP7

    		HIV Infection
    ZP7 (compound 7c) is a potent anti-HIV-1 agent with an EC50 of 36.4nM. ZP7 can be utilized in HIV-1 research .
    ZP7
  • HY-158419
    PB(OH)3

    		HIV Infection
    PB(OH)3 is an anti-HIV-1 agent that can be used in antiviral research .
    PB(OH)3
  • HY-161924
    HIV-1 inhibitor-73

    		HIV Infection
    HIV-1 inhibitor-73 (compound 13c) is a potent anti-HIV-1 agent, against the whole tested viral panel with EC50 ranging from 4.68 to 229 nM .
    HIV-1 inhibitor-73
  • HY-N10801
    Salvianan A

    		HIV Infection
    1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) is a potent anti-HIV-1 agent .
    Salvianan A
  • HY-167945
    AMD-3329

    		HIV CXCR Infection
    AMD-3329 is a potent and selective anti-HIV-1 and HIV-2 agent, exhibiting activity by inhibiting virus replication through binding to the chemokine receptor CXCR4, which serves as a co-receptor for the entry of X4 viruses.
    AMD-3329
  • HY-116528
    GCA-186

    		HIV Infection
    GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1, 180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively .
    GCA-186
  • HY-117205
    GS-7339

    		HIV Infection
    GS-7339 is a diastereomer of GS-7171 (HY-136555) and is an anti-HIV-1 agent with an IC50 of 0.06 μM. GS-7339 can be used for the research of HIV-1 infection .
    GS-7339
  • HY-182514
    BMMP

    		HIV hnRNP Infection Cancer
    BMMP is an anti-HIV-1 agent and hnRNP M modulator. BMMP modulates hnRNP M function to suppress CD44 mRNA expression. BMMP induces abnormal uncoating of the HIV viral core at the post-entry step. BMMP suppresses migration of TGF-β-stimulated lung carcinoma cells. BMMP suppresses HIV-1 reverse transcription and replication without inhibiting virion release. BMMP exerts anti-HIV-1 activity via a mechanism distinct from CA protein-binding heterocyclic compounds. BMMP can be used for the research of human immunodeficiency virus infection and non-small cell lung cancer .
    BMMP
  • HY-182376
    JRC-I-191

    		HIV Infection
    JRC-I-191 is an anti-HIV-1 agent. JRC-I-191 inhibits HIV-1 YU-2 entry into cells. JRC-I-191 does not inhibit infection of cells by amphotropic murine leukemia virus. JRC-I-191 can be used for the research of HIV-1 infection .
    JRC-I-191
  • HY-115488
    BNM-III-170 free base

    		HIV Infection
    BNM-III-170 free base, CD4-mimeticcompound, is an anti-HIV-1 agent. BNM-III-170 free base, binds to the Phe43 cavity of HIV 1 gp120. BNM-III-170 can inhibits HIV-1 viral entry into target cells. BNM-III-170 free base, can be used for the research of HIV-1 infection .
    BNM-III-170 free base
  • HY-104012R
    Islatravir (Standard)

    MK-8591 (Standard)

    		 Reference Standards HIV Reverse Transcriptase Infection Inflammation/Immunology
    Islatravir (Standard) is the analytical standard of Islatravir (HY-104012). This product is intended for research and analytical applications. Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Islatravir (Standard)
  • HY-183925
    Redoxal

    		HIV Dihydroorotate Dehydrogenase Infection
    Redoxal is a dihydroorotate dehydrogenase (DHODH) inhibitor and anti-HIV-1 agent. Redoxal induces intracellular pyrimidine depletion by inhibiting the de novo pyrimidine biosynthesis pathway, enhances the protein stability of APOBEC3G (A3G), upregulates the abundance of A3G protein in cells and progeny viral particles, thereby strengthening the host endogenous antiviral restriction mediated by A3G . Redoxal selectively targets DHOdehase at the mitochondrial level, with an IC50 of 430 nM for inhibiting DHO oxidation in human mitochondria and an IC50 of 910 nM in rat mitochondria . Redoxal can be used in studies related to HIV-1 infection .
    Redoxal

온라인 문의

Your information is safe with us. * Required Fields.

호칭

  

Country or Region *

고객명 *

 

회사명 *

Department *

     

메일주소 *

 

상품명 *

Cat. No.

  

Requested quantity *

전화번호 *

     

비고

온라인 문의

Inquiry Information

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent: