JRC-I-191
JRC-I-191 is an anti-HIV-1 agent. JRC-I-191 inhibits HIV-1 YU-2 entry into cells. JRC-I-191 does not inhibit infection of cells by amphotropic murine leukemia virus. JRC-I-191 can be used for the research of HIV-1 infection.
For research use only. We do not sell to patients.
- CAS No.: 1098209-30-3
- Formula: C17H23ClFN3O2
- Molecular Weight:355.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIV-1 |
JRC-I-191 (Compound 3) inhibits HIV-1 YU-2 entry into Cf2Th-CD4/CCR5 cells with an IC50 of 54.4 μM, does not inhibit A-MLV infection[1].
JRC-I-191 binds to HIV-1 YU2 gp120 with a Kd of 0.76 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1098209-30-3
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Molecular Weight 355.83
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Formula C17H23ClFN3O2
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SMILES
O=C(C(NC1CC(C)(C)NC(C)(C1)C)=O)NC2=CC=C(C(F)=C2)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)