1. Anti-infection
  2. HIV
  3. BNM-III-170 free base

BNM-III-170 free base, CD4-mimeticcompound, is an anti-HIV-1 agent. BNM-III-170 free base, binds to the Phe43 cavity of HIV 1 gp120. BNM-III-170 can inhibits HIV-1 viral entry into target cells. BNM-III-170 free base, can be used for the research of HIV-1 infection.

For research use only. We do not sell to patients.

BNM-III-170 free base

BNM-III-170 free base Chemical Structure

CAS No. : 1859189-54-0

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Description

BNM-III-170 free base, CD4-mimeticcompound, is an anti-HIV-1 agent. BNM-III-170 free base, binds to the Phe43 cavity of HIV 1 gp120. BNM-III-170 can inhibits HIV-1 viral entry into target cells. BNM-III-170 free base, can be used for the research of HIV-1 infection[1].

IC50 & Target[1]

HIV-1

 

In Vitro

BNM-III-170 free base, inhibits HIV 1 JR FL strain entry into Cf2Th CD4/CCR5 cells with an IC50 of 14.5 μM[1].
BNM-III-170 free base, inhibts various HIV-1 viral strains with IC50 values of 9-200 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

446.91

Formula

C21H24ClFN6O2

CAS No.
SMILES

N(C(C(NC1=CC(F)=C(Cl)C=C1)=O)=O)[C@H]2C=3C(C[C@@H]2CNC(=N)N)=CC(CNC)=CC3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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BNM-III-170 free base Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BNM-III-170 free base
Cat. No.:
HY-115488
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