AMD-3329
AMD-3329 is a potent and selective anti-HIV-1 and HIV-2 agent, exhibiting activity by inhibiting virus replication through binding to the chemokine receptor CXCR4, which serves as a co-receptor for the entry of X4 viruses.
For research use only. We do not sell to patients.
- CAS No.: 170861-87-7
- Formula: C34H50N8
- Molecular Weight:570.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | EC50 |
0.8 nM
Compound: 17; AMD3329
|
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect after 5 days by MTT assay
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect after 5 days by MTT assay
|
[PMID: 26974376] |
Chemical Information
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CAS No. 170861-87-7
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Molecular Weight 570.81
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Formula C34H50N8
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SMILES
C12=CC=CC(CCNCCN(CCNCC2)CC3=CC=C(CN4CCNCCC5=CC=CC(CCNCC4)=N5)C=C3)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)