AMD-3329
AMD-3329 is a potent and selective anti-HIV-1 and HIV-2 agent, exhibiting activity by inhibiting virus replication through binding to the chemokine receptor CXCR4, which serves as a co-receptor for the entry of X4 viruses.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 170861-87-7
- Formel: C34H50N8
- Molecular Weight:570.81
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | EC50 |
0.8 nM
Compound: 17; AMD3329
|
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect after 5 days by MTT assay
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect after 5 days by MTT assay
|
[PMID: 26974376] |
Chemical Information
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CAS. Nr. 170861-87-7
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Molecular Weight 570.81
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Formel C34H50N8
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SMILES
C12=CC=CC(CCNCCN(CCNCC2)CC3=CC=C(CN4CCNCCC5=CC=CC(CCNCC4)=N5)C=C3)=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)