Search Result

Results for "

anti-osteoporotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Antibiotic (1) Apoptosis (1) Bacterial (3) CaSR (1) CGRP Receptor (1) Endothelin Receptor (1) Estrogen Receptor/ERR (3) Phosphatase (1) PPAR (2) Prostaglandin Receptor (2) Reactive Oxygen Species (3) SARS-CoV (2) Wnt (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Endocrinology (4) Infection (3) Inflammation/Immunology (5) Metabolic Disease (8) Neurological Disease (2)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0806

Sweroside

Others Metabolic Disease

Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect .
HY-100304A

KW-8232

Prostaglandin Receptor SARS-CoV Metabolic Disease Endocrinology

KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2 .

Sweroside	Others	Metabolic Disease
Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect .

KW-8232	Prostaglandin Receptor SARS-CoV	Metabolic Disease Endocrinology
KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2 .

HY-149943

PAP-IN-2	Others	Inflammation/Immunology
PAP-IN-2 (Compound 35) is a purple acid phosphatase (PAP) inhibitor (K_is: 186 nM). PAP-IN-2 can be used for development of anti-osteoporotic compounds .

HY-149942

PAP-IN-1	Others	Others
PAP-IN-1 (compound 28) is an inhibitor of purple acid phosphatases (PAPs), a ubiquitous binuclear metallohydrolase. PAP-IN-1 inhibits mammalian PAP with K_i value of 168 nM. PAP-IN-1 targets to pig PAP with K_ic value of 0.17 μM. PAP inhibitors can be used for research of anti-osteoporotic drugs .

HY-121300

Kendomycin (-)-TAN2162	Antibiotic Bacterial Endothelin Receptor CGRP Receptor	Infection Cancer
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent .

HY-100304

KW-8232 free base	Prostaglandin Receptor SARS-CoV	Metabolic Disease Endocrinology
KW-8232 free base, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2 .

HY-112920

TM-25659

Others Metabolic Disease

TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities .

TM-25659	Others	Metabolic Disease
TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities .

HY-A0037

Lasofoxifene CP-336156	Estrogen Receptor/ERR	Inflammation/Immunology Cancer
Lasofoxifene (CP-336156) is an orally active and selective estrogen receptor modulator (SERM). Lasofoxifene exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene can be used for research of breast cancer and postmenopausal osteoporosis .

HY-A0038

Lasofoxifene tartrate 3 Publications Verification CP-336156 tartrate	Estrogen Receptor/ERR	Endocrinology Cancer
Lasofoxifene (CP-336156) tartrate is an orally active and selective estrogen receptor modulator (SERM) . Lasofoxifene tartrate exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene tartrate can be used for the research of breast cancer and postmenopausal osteoporosis .

HY-107794

Clodronate disodium tetrahydrate Disodium clodronate tetrahydrate	Others	Neurological Disease Inflammation/Immunology Cancer
Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl ^- competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC₅₀ of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain .

HY-N7326

Latinone

Others Cardiovascular Disease

Latinone, a neoflavonoid isolated from Dalbergia cochinchinensis, has antiosteoporotic activity .
HY-N0259

Epimedin B

2 Publications Verification

Epmedin B
Others Others

Epimedin B, a component extracted from Epimedii Folium, is reported to have antiosteoporotic activity.
HY-138211

BE-26263

Estrogen Receptor/ERR Metabolic Disease Endocrinology

BE-26263, an antiosteoporotic agent that can be isolated from Scedosporium apiospermum, possesses estrogenic effect .

Latinone	Others	Cardiovascular Disease
Latinone, a neoflavonoid isolated from Dalbergia cochinchinensis, has antiosteoporotic activity .

Epimedin B 2 Publications Verification Epmedin B	Others	Others
Epimedin B, a component extracted from Epimedii Folium, is reported to have antiosteoporotic activity.

BE-26263	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
BE-26263, an antiosteoporotic agent that can be isolated from Scedosporium apiospermum, possesses estrogenic effect .

HY-N8789

2-Hydroxymethyl-3-hydroxyanthraquinone	Phosphatase	Others
2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity .

HY-119868

Butaxamine Butoxamin	Adrenergic Receptor	Metabolic Disease
Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity .

HY-N7646

Curculigoside B	Others	Others
Curculigoside B, a phenolic glycoside isolated from Curculigo orchioides, enhances the osteoblast proliferation, decreases the area of bone resorption pit, osteoclastic formation and TRAP activity. Antiosteoporotic and antioxidative activities .

HY-N0020

Echinacoside Maximum Cited Publications 7 Publications Verification	Wnt Reactive Oxygen Species	Neurological Disease
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

HY-124081

N-Oleoyl-L-serine	Apoptosis	Metabolic Disease
N-Oleoyl-L-Serine is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development .

HY-N0393

Glabridin 1 Publications Verification	PPAR Reactive Oxygen Species Bacterial	Infection Inflammation/Immunology Cancer
Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

HY-N0393R

Glabridin (Standard)	PPAR Reactive Oxygen Species Bacterial	Infection Inflammation/Immunology Cancer
Glabridin (Standard) is the analytical standard of Glabridin. This product is intended for research and analytical applications. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

HY-17397

Strontium Ranelate 2 Publications Verification Distrontium renelate; S12911	CaSR	Metabolic Disease
Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .

N-Oleoyl-L-serine	Apoptosis	Metabolic Disease
N-Oleoyl-L-Serine is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development .

Sweroside	Filago spathulata Presl. Structural Classification Monophenols Classification of Application Fields Labiatae Phenols Metabolic Disease Plants Disease Research Fields	Others
Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect .

Epimedin B 2 Publications Verification Epmedin B	Flavonols Monophenols Flavonoids Classification of Application Fields Source classification Other Diseases Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields	Others
Epimedin B, a component extracted from Epimedii Folium, is reported to have antiosteoporotic activity.

Curculigoside B	Curculigo orchioides Gaertn. Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields Amaryllidaceae	Others
Curculigoside B, a phenolic glycoside isolated from Curculigo orchioides, enhances the osteoblast proliferation, decreases the area of bone resorption pit, osteoclastic formation and TRAP activity. Antiosteoporotic and antioxidative activities .

Latinone	Cardiovascular Disease Quinones Monophenols other families Classification of Application Fields Source classification Phenols Plants Phenanthrenequinones Disease Research Fields	Others
Latinone, a neoflavonoid isolated from Dalbergia cochinchinensis, has antiosteoporotic activity .

2-Hydroxymethyl-3-hydroxyanthraquinone	Quinones Anthraquinones Rubiaceae Plants Morinda officinalis How	Phosphatase
2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity .

Echinacoside Maximum Cited Publications 7 Publications Verification	Structural Classification Simple Phenylpropanols Source classification Cistanche deserticola Ma Phenols Polyphenols Orobanchaceae Phenylpropanoids Plants	Wnt Reactive Oxygen Species
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

Glabridin 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Plants Infection Flavonoids Leguminosae Phenols Polyphenols Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones	PPAR Reactive Oxygen Species Bacterial
Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

Glabridin (Standard)	Infection Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Plants Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	PPAR Reactive Oxygen Species Bacterial
Glabridin (Standard) is the analytical standard of Glabridin. This product is intended for research and analytical applications. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.

anti-osteoporotic

Inhibitors & Agonists

Peptides

NaturalProducts

Natural
Products