2-Hydroxymethyl-3-hydroxyanthraquinone
2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity.
For research use only. We do not sell to patients.
- CAS No.: 68243-30-1
- Formula: C15H10O4
- Molecular Weight:254.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
TRAP[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
3 μM
Compound: 21
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Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
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[PMID: 21973054] |
2-Hydroxymethyl-3-hydroxyanthraquinone (0.1-10 μM; 48 h) dose-dependently inhibits osteoclastic TRAP activity, and reduces osteoclastic bone resorption pit area on bone slices[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 68243-30-1
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Molecular Weight 254.24
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Formula C15H10O4
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SMILES
O=C1C2=C(C=CC=C2)C(C3=CC(CO)=C(O)C=C13)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Hydroxymethyl-3-hydroxyanthraquinone Related Classifications
HY-N8789 Related Classifications
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