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Art. -Nr.: HY-N8789

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2-Hydroxymethyl-3-hydroxyanthraquinone

2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity.

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CAS. Nr.: 68243-30-1
Formel: C₁₅H₁₀O₄
Molecular Weight:254.24

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

2-Hydroxymethyl-3-hydroxyanthraquinone Chemical Structure

CAS. Nr.: 68243-30-1

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity^[1].

IC₅₀ & Target

TRAP^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	3 μM Compound: 21	Cytotoxicity against human HeLa cells after 48 hrs by SRB assay Cytotoxicity against human HeLa cells after 48 hrs by SRB assay	[PMID: 21973054]

In Vitro

2-Hydroxymethyl-3-hydroxyanthraquinone (0.1-10 μM; 48 h) dose-dependently inhibits osteoclastic TRAP activity, and reduces osteoclastic bone resorption pit area on bone slices^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 68243-30-1
Molecular Weight 254.24
Formel C₁₅H₁₀O₄
SMILES

O=C1C2=C(C=CC=C2)C(C3=CC(CO)=C(O)C=C13)=O
Structure Classification
- Quinones
- Anthraquinones
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wu YB, et al. Antiosteoporotic activity of anthraquinones from Morinda officinalis on osteoblasts and osteoclasts. Molecules. 2009 Jan 23;14(1):573-83. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

2-Hydroxymethyl-3-hydroxyanthraquinone

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Biologische Aktivität
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- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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2-Hydroxymethyl-3-hydroxyanthraquinone

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

2-Hydroxymethyl-3-hydroxyanthraquinone Related Classifications

HY-N8789 Related Classifications