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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
anticoagulant effects
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "anticoagulant effects" in MCE Product Catalog:
33
33 Publications Verification
Cat. No.: HY-D0836
CAS No.: 25102-12-9
Synonyms: Ethylenediaminetetraacetic acid dipotassium dihydrate
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11 Cited Publications
Cat. No.: HY-P1929
CAS No.: 128270-60-0
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11
11 Cited Publications
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9
9 Cited Publications
Cat. No.: HY-114164H
CAS No.: 9002-04-4
Synonyms: EC 3.4.21.5 (Lyophilized); Human Alpha Thrombin (Lyophilized)
Research Areas:
Human α-Thrombin (EC 3.4.21.5; Human Alpha Thrombin) (Lyophilized) is a terminal serine protease in the coagulation cascade, as well as a potent physiological platelet agonist and fibrin-generating enzyme in vivo. Human α-Thrombin catalyzes the conversion of fibrinogen to fibrin for blood clot formation, and activates platelet aggregation by cleaving the protease-activated receptors PAR1 (major) (Kd = 1 nM) and PAR4 (minor) on the platelet surface to expose tethered ligands. Human α-Thrombin also amplifies coagulation via positive feedback by activating coagulation factors V, VIII, XI (FV/FVIII/FXI), and switches to activate protein C to exert anticoagulant effects after binding to thrombomodulin .
This product is in a freeze-dried form.
This product is in a freeze-dried form.
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Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
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4 Cited Publications
Synonyms: BIBR 1048MS; Dabigatran etexilate methanesulfonate
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Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
Synonyms: WL 108366
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Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .
Cat. No.: HY-P99794
CAS No.: 2056878-75-0
Synonyms: BAY 1213790
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Cat. No.: HY-N1400
CAS No.: 80952-71-2
Category:
Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer
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Cat. No.: HY-18660
CAS No.: 1438492-26-2
Synonyms: PER977
Research Areas:
Ciraparantag (PER977) is a thrombin and factor Xa inhibitor. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban .
Cat. No.: HY-P2933
CAS No.: 42617-41-4
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Activated protein C is an anticoagulant targeting coagulation factors Va and VIIIa. Activated protein C demonstrates cytoprotective effects through binding to endothelial cell protein C receptor (EPCR) and protease-activated receptor-1 (PAR-1), regulating gene expression, anti-inflammation, anti-apoptosis, and stabilizing endothelial barriers. Activated protein C is promising for research of diseases such as severe sepsis and ischemic stroke .
Cat. No.: HY-P4325
CAS No.: 109528-50-9
Cat. No.: HY-108739
CAS No.: 1362509-93-0
Synonyms: BI 655075
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Cat. No.: HY-10274R
CAS No.: 211915-06-9
Synonyms: BIBR 1048 (Standard)
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Dabigatran etexilate (Standard) is the analytical standard of Dabigatran etexilate. This product is intended for research and analytical applications. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
Synonyms: YM150
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Darexaban (YM150) is a potent, selective and orally active factor Xa (FXa) inhibitor with an IC50 of 54.6 nM. Darexaban shows high selectivity against other related serine proteases, such as trypsin, thrombin, and kallikrein. Darexaban has anticoagulant and antithrombotic effects .
Cat. No.: HY-15759A
CAS No.: 159668-20-9
Synonyms: Ro 46-6240 hydrate; Ro 46-6240/010 hydrate
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Napsagatran (Ro 46-6240) hydrate is a potent thrombin inhibitor. Napsagatran hydrate exhibits anticoagulant effects in vitro and in vivo. Napsagatran hydrate can be used in antithrombotic research [1][2].
Cat. No.: HY-172316
CAS No.: 2915316-40-2
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BAY 3389934 is a selective dual inhibitor of factor IIa and factor Xa, with an IC50 of 4.9 nM for factor IIa and an IC50 of 0.66 nM for factor Xa. BAY 3389934 directly inhibits the activities of factor IIa and factor Xa and regulates the common coagulation pathway. BAY 3389934 exhibits anticoagulant and organ-protective effects. BAY 3389934 can be used in the research of sepsis and coagulopathy .
Cat. No.: HY-172231
CAS No.: 110346-23-1
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Hexolame is an estrogen receptors agonist with dual anticoagulant and estrogenic properties. Hexolame binds to estrogen receptors to induce anticoagulant effects by modulating clotting factors or platelet activity. Hexolame is promising for research of prostatic cancer and prevention of thrombosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
