2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. Osocimab

Osocimab  (Synonyms: BAY 1213790)

Cat. No.: HY-P99794 Purity: 95.00%
COA

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Osocimab (BAY 1213790), an anti-FXIa antibody (Ki=2.4 nM; EC50=0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects.

For research use only. We do not sell to patients.

Osocimab Chemical Structure

Osocimab Chemical Structure

CAS No. : 2056878-75-0

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Osocimab Related Antibodies

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Description

Osocimab (BAY 1213790), an anti-FXIa antibody (Ki=2.4 nM; EC50=0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects[1].

In Vitro

Osocimab (1.4 nM-1 μM; 30 min) inhibits thrombin generation, and also inhibits FXIa-mediated activation of FIX (FIX conversion) (IC50=16 nM) and FXIa mediated substrate cleavage (IC50=1.2 nM) in human plasma[1].
Osocimab (22.05 mg/mL) inhibits intrinsic pathway-mediated activation of the coagulation cascade[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Osocimab Related Antibodies
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CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Osocimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.00%

COA (231 KB)

Handling Instructions (2659 KB)
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Osocimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Osocimab2056878-75-0BAY 1213790BAY1213790BAY-1213790Factor XaFxaInhibitorinhibitorinhibit

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