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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
arachidonic acid (AA)
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "arachidonic acid (AA)" in MCE Product Catalog:
1
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Phospholipase A2 (PLA2) is a calcium-dependent, heat-stable enzyme that catalyzes the hydrolysis of glycerophospholipids at the sn-2 position of cellular membranes, thereby releasing Arachidonic Acid (AA) (HY-109590). Phospholipase A2 is a key mediator in the biosynthesis of pro-inflammatory lipid mediators, critically involved in inflammatory processes. Phospholipase A2 can be used for cardiovascular and inflammatory diseases research .
Cat. No.: HY-124404A
CAS No.: 54397-83-0
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Synonyms: 7-HCA; Umbelliferyl Arachidonate; 7-HC-arachidonate
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7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer .
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ALOX15-IN-1 (compound 8b) is a potent inhibitor of the linoleate oxygenase activity of rabbit and human ALOX15 with IC50s of 0.04 and 2.06 μM for ALOX15 0rthologs linoleic acid (LA) and arachidonic acid (AA), respectively .
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CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM . PMNL: polymorphonuclear leukocytes; AA: arachidonic acid
Cat. No.: HY-116246
CAS No.: 127708-42-3
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5(S)-HETE lactone is an arachidonic acid (AA) metabolite .
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ALOX15-IN-2 (compound 8a) is a potent inhibitor of the linoleate oxygenase activity of rabbit and human ALOX15 with IC50s of 1.55 and 2.79 μM for ALOX15 0rthologs linoleic acid (LA) and arachidonic acid (AA), respectively .
Synonyms: 5-iso Prostaglandin F2α-VI
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(±)5-iPF2α-VI (5-iso Prostaglandin F2α-VI) is the racemate of 5-iPF2α-VI. 5-iPF2α-VI is a regioisomeric isoprostane formed from arachidonic acid (AA) and is a biomarker of oxidative stress .
Cat. No.: HY-W013214
CAS No.: 1808-26-0
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Target:
Cat. No.: HY-150092
CAS No.: 123931-39-5
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Cat. No.: HY-N2892
CAS No.: 97399-91-2
Synonyms: Aristololactam A IIIa; Sch 546909
Category:
Fissistigma balansae (A. DC.) Merr. Antibiotics Plants Annonaceae Disease Research Anticancer Other Antibiotics
Target:
Cat. No.: HY-173534
Synonyms: AA sulfonate sodium
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Arachidonic acid sulfonate (AA sulfonate) sodium is a derivative of Arachidonic acid (HY-109590) containing a sulfonate group.
Cat. No.: HY-119735
CAS No.: 17015-43-9
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Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .
Cat. No.: HY-N12514
CAS No.: 19275-51-5
Category:
Flavonoids Plants Moraceae Other Flavonoids Morus alba Linn.
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Cat. No.: HY-134556
CAS No.: 17348-76-4
Category:
Flavonoids Leguminosae Mimosa pudica Linn. Flavonones Plants
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Trifenagrel is an orally active platelet aggregation inhibitor that inhibits the inducing effects of arachidonic acid (AA) and collagen. The ED50s of trifenagrel for inhibiting AA- and collagen-induced platelet aggregation in guinea pigs were 1.4 mg/kg and 9.4 mg/kg, respectively .
Cat. No.: HY-105120A
CAS No.: 87248-13-3
Synonyms: GR 32191 hydrochloride
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Vapiprost hydrochloride (GR 32191 hydrochloride) is a thromboxane A2 receptor antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1×10 -8 M .
Cat. No.: HY-105120
CAS No.: 85505-64-2
Synonyms: GR 32191
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Research Areas:
Vapiprost (GR 32191) is a thromboxane A2 receptor (TXA2 Receptor) antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1×10 -8 M .
Cat. No.: HY-W013214S
Cat. No.: HY-131626
CAS No.: 26198-80-1
Synonyms: 1a,1b-Dihomo PGE2
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1a,1b-Dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid. 1a,1b-Dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid. This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
