ALOX15-IN-1
Based on 1 Customer Validation
ALOX15-IN-1 (compound 8b) is a potent inhibitor of the linoleate oxygenase activity of rabbit and human ALOX15 with IC50s of 0.04 and 2.06 μM for ALOX15 0rthologs linoleic acid (LA) and arachidonic acid (AA), respectively.
For research use only. We do not sell to patients.
- Purity: 98.01%
- CAS No.: 2764818-24-6
- Formula: C24H31N3O5S
- Molecular Weight:473.59
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2764818-24-6
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Appearance Solid
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Molecular Weight 473.59
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Formula C24H31N3O5S
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Color Off-white to light yellow
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SMILES
O=S(NC1=C(C=CC(C2=CC3=C(C=CC=C3)N2)=C1)OC)(NC(OCCCCCCCC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (211.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1115 mL | 10.5577 mL | 21.1153 mL | 52.7883 mL |
| 5 mM | 0.4223 mL | 2.1115 mL | 4.2231 mL | 10.5577 mL | |
| 10 mM | 0.2112 mL | 1.0558 mL | 2.1115 mL | 5.2788 mL | |
| 15 mM | 0.1408 mL | 0.7038 mL | 1.4077 mL | 3.5192 mL | |
| 20 mM | 0.1056 mL | 0.5279 mL | 1.0558 mL | 2.6394 mL | |
| 25 mM | 0.0845 mL | 0.4223 mL | 0.8446 mL | 2.1115 mL | |
| 30 mM | 0.0704 mL | 0.3519 mL | 0.7038 mL | 1.7596 mL | |
| 40 mM | 0.0528 mL | 0.2639 mL | 0.5279 mL | 1.3197 mL | |
| 50 mM | 0.0422 mL | 0.2112 mL | 0.4223 mL | 1.0558 mL | |
| 60 mM | 0.0352 mL | 0.1760 mL | 0.3519 mL | 0.8798 mL | |
| 80 mM | 0.0264 mL | 0.1320 mL | 0.2639 mL | 0.6599 mL | |
| 100 mM | 0.0211 mL | 0.1056 mL | 0.2112 mL | 0.5279 mL |