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eriodictyol

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

16

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0636
    Eriocitrin
    5 Publications Verification

    eriodictyol 7-rutinoside; eriodictyol 7-O-rutinoside

    		 Apoptosis Cancer
    Eriocitrin is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria .
    Eriocitrin
  • HY-N0637
    Eriodictyol
    10+ Cited Publications

    Huazhongilexone

    		 Melanocortin Receptor TRP Channel Infection Inflammation/Immunology
    Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases .
    Eriodictyol
  • HY-N0637A
    (±)-Eriodictyol

    (±)-Huazhongilexone; Dihydroluteolin

    		 Melanocortin Receptor TRP Channel Metabolic Disease
    (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases .
    (±)-Eriodictyol
  • HY-N3847
    Eriodictyol-7-O-glucoside

    eriodictyol 7-O-β-D-glucoside

    		 Keap1-Nrf2 Neurological Disease
    Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC50 values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke .
    Eriodictyol-7-O-glucoside
  • HY-N9686
    Caffeoyl-CoA

    		Others Others Inflammation/Immunology
    Caffeoyl-CoA is a substrate of Chalcone synthase derived from rye with a Km value of 1.45 μM .
    Caffeoyl-CoA
  • HY-N2754
    Sternbin

    eriodictyol 7-methyl ether; 7-O-Methyleriodictyol

    		 Bacterial Infection Cardiovascular Disease
    Sternbin (Eriodictyol 7-methyl ether) is a flavanone and antibacterial agent. Sternbin can be isolated from Heliotropium sinuatum. Sternbin has antibacterial activity against a wide range of bacteria. Sternbin has antiviral activity against infectious salmon anemia virus (ISAV). Sternbin inhibits the contraction of isolated rat smooth muscle .
    Sternbin
  • HY-N0636R
    Eriocitrin (Standard)

    eriodictyol 7-rutinoside (Standard); eriodictyol 7-O-rutinoside (Standard)

    		 Reference Standards Apoptosis Cancer
    Eriocitrin (Standard) is the analytical standard of Eriocitrin. This product is intended for research and analytical applications. Eriocitrin is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria .
    Eriocitrin (Standard)
  • HY-N9551
    Eriodictyol chalcone

    		Cytochrome P450 Parasite COX Lipoxygenase Infection Neurological Disease Cancer
    Eriodictyol chalcone is an antioxidant that inhibits multiple key enzymes including 5-LOX (IC50=0.043 μM), aromatase/CYP19A1 (IC50=2.8 μM), PTPase 1B (IC50=1.26 μM), and COX (IC50=34 μM). Eriodictyol chalcone exhibits excellent free radical scavenging activity. Eriodictyol chalcone not only inhibits the growth of plasmodia and enhances the efficacy of Artemisinin (HY-B0094), but also reduces depression-like behaviors in animal models. Eriodictyol chalcone serves as a biosynthetic precursor for Aureusidin (HY-N9834). Eriodictyol chalcone is a potential dietary supplement and herbicide, and it can be applied to research on malaria, depression, breast cancer and other related diseases .
    Eriodictyol chalcone
  • HY-N12025
    Eriodictyol 7-O-glucuronide

    		Others Others
    Eriodictyol 7-O-glucuronide is a flavonoid isolated from Cosmos sulphureus .
    Eriodictyol 7-O-glucuronide
  • HY-N0637AR
    (±)-Eriodictyol (Standard)

    (±)-Huazhongilexone (Standard); Dihydroluteolin (Standard)

    		 Reference Standards Melanocortin Receptor TRP Channel Metabolic Disease
    3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases .
    (±)-Eriodictyol (Standard)
  • HY-N9112
    Eriodictyol 7, 3'-dimethyl ether

    		Bacterial Infection
    Eriodictyol 7, 3'-dimethyl ether (compound 11) is the first flavonoid extract from B. riparia with antioxidant and antibacterial activity .
    Eriodictyol 7, 3'-dimethyl ether
  • HY-N13787
    Eriodictyol 7-O-methylglucuronide

    		Drug Derivative Others
    Eriodictyol 7-O-methylglucuronide is a natural flavonoid.
    Eriodictyol 7-O-methylglucuronide
  • HY-N16924
    Eriodictyol 7-O-β-D-glucuronide ethyl ester

    		Drug Derivative Others
    Eriodictyol 7-O-β-D-glucuronide ethyl ester is a natural flavonoid.
    Eriodictyol 7-O-β-D-glucuronide ethyl ester
  • HY-N18319
    (±)-Eriodictyol 7-O-β-D-pyranoglucuronide

    		Drug Derivative Others
    (±)-Eriodictyol 7-O-β-D-pyranoglucuronide is a flavonoid glycoside found in the leaves of Pyrrosia petiolosa .
    (±)-Eriodictyol 7-O-β-D-pyranoglucuronide
  • HY-N13190
    (2R)-Eriodictyol-7-O-β-D-glucopyranoside

    		Others Others
    (2R)-Eriodictyol-7-O-β-D-glucopyranoside (compound 3a) is a flavonoid glucoside isolated from Balanophora involucrata .
    (2R)-Eriodictyol-7-O-β-D-glucopyranoside
  • HY-N17719
    (2S)-Eriodictyol-5-O-β-D-glucopyranoside

    		Others Others
    (2S)-Eriodictyol-5-O-β-D-glucopyranoside (Compound 1b) is a type of flavanone glucoside compound, which can be found in Balanophora involucrate Hook. f .
    (2S)-Eriodictyol-5-O-β-D-glucopyranoside

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