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Results for "

long-chain acyl-CoA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (2) Acetyl-CoA Carboxylase (1) ACSL Family (3) Biochemical Assay Reagents (12) Carnitine Palmitoyltransferase (CPT) (1) Drug Derivative (1) Endogenous Metabolite (17) Ferroptosis (1) Isotope-Labeled Compounds (4) Parasite (1) Reference Standards (5)
By Research Areas:	Cancer (8) Cardiovascular Disease (3) Infection (1) Inflammation/Immunology (3) Metabolic Disease (20) Neurological Disease (9)
Oligonucleotides:	Cationic Lipids (1)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

GMP Molecules

Targets Recommended: ELOVL Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0399

L-Carnitine Maximum Cited Publications 20 Publications Verification (R)-Carnitine; Levocarnitine	Endogenous Metabolite	Neurological Disease Cancer
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-N6707

Triacsin C 5+ Cited Publications WS 1228A; FR 900190	ACSL Family Parasite	Infection Cardiovascular Disease
Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

HY-173432

LIBX-A401	ACSL Family Ferroptosis	Neurological Disease Cancer
LIBX-A401 is a selective long-chain acyl-CoA synthetase 4 (ACSL4) inhibitor with a human IC₅₀ values of 0.38 μM and a K_d of 0.72 μM. LIBX-A401 binds to ACSL4 in an ATP-dependent manner, stabilizes the C-terminal domain, alters the fatty acid gate region, and interacts with residues A329 and Q302 within the fatty acid binding site. LIBX-A401 exhibits anti-ferroptosis properties in cells. LIBX-A401 can be used for the researches of cancer and parkinson's disease .

HY-B2246

L-Carnitine hydrochloride Maximum Cited Publications 20 Publications Verification (R)-Carnitine hydrochloride; Levocarnitine hydrochloride	Endogenous Metabolite	Metabolic Disease Cancer
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-113201

Tetradecanoylcarnitine	Endogenous Metabolite	Neurological Disease
Tetradecanoylcarnitine is an acylcarnitine involved in mitochondrial β-oxidation of long-chain saturated fatty acids and fatty acid metabolism. Tetradecanoylcarnitine serves as a biomarker for *very long-chain* acyl-CoA dehydrogenase** deficiency and MPTP (HY-15608)-induced Parkinson's disease. Tetradecanoylcarnitine exhibits a characteristic significant elevation in plasma levels in patients with sarcopenia, including those complicated with hypertension, and this elevation is closely associated with an increased risk of death. Tetradecanoylcarnitine is widely used in research on the pathological mechanisms of diseases such as Parkinson's disease and sarcopenia .

HY-W105518

L-Carnitine tartrate 15+ Cited Publications	Endogenous Metabolite	Neurological Disease
L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

HY-177705

ACSL5-IN-2	ACSL Family Drug Derivative	Metabolic Disease Cancer
ACSL5-IN-2 (Compound B) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-2 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-2 can inhibit cancer cells growth. ACSL5-IN-2 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis .

HY-B2246S

L-Carnitine-d9 chloride 1 Publications Verification (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B0399S

L-Carnitine-d9 1 Publications Verification (R)-Carnitine-d₉; Levocarnitine-d₉	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Carnitine-d₉ is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-107396

YM-750	Acyltransferase	Cardiovascular Disease
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC₅₀=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .

HY-B0399R

L-Carnitine (Standard) (R)-Carnitine (Standard); Levocarnitine (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease Cancer
L-Carnitine (Standard) is the analytical standard of L-Carnitine. This product is intended for research and analytical applications. L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-131303

Heptadecanoyl Coenzyme A Heptadecanoyl-CoA	Biochemical Assay Reagents	Metabolic Disease
Heptadecanoyl Coenzyme A (Heptadecanoyl-CoA), long-chain acyl-coenzymes A (acyl-CoAs) (LCACoA), is an intermediate in lipid metabolism. Heptadecanoyl Coenzyme A can be used for the research of glucose metabolism .

HY-W612338

9-Oxononanoic acid 9-ONA	Acetyl-CoA Carboxylase	Inflammation/Immunology
9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis .

HY-E70278

(9Z-Octadecenyl)-CoA triammonium	Biochemical Assay Reagents	Metabolic Disease
(9Z-Octadecenyl)-CoA triammonium is a coenzyme. (9Z-Octadecenyl)-CoA triammonium is a long-chain acyl-CoA esters. Long-chain acyl-CoA esters are involved in regulation of fatty acid synthesis, enzyme systems, vesicle trafficking, ion channels and ion pumps .

HY-E70273

Tetradecyl-CoA triammonium	Endogenous Metabolite	Others
Tetradecyl-CoA triammonium is a long-chain acyl-CoA .

HY-CE01045

3-Hydroxytetracosanoyl-CoA 3-Hydroxytetracosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxytetracosanoyl-CoA (3-Hydroxytetracosanoyl-coenzyme A) is a very long-chain fatty acyl-CoA.

HY-B0399S2

L-Carnitine-13C3 (R)-Carnitine-¹³C3; Levocarnitine-¹³C3	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Cancer
L-Carnitine- ¹³C₃ ((R)-Carnitine- ¹³C₃) is the ¹³C--labeled L-Carnitine (HY-B0399). L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-E70276

Heneicosanoyl-CoA	Endogenous Metabolite	Metabolic Disease
Heneicosanoyl-CoA is a substrate of Very long-chain acyl-CoA dehydrogenase (VLCAD) in the anaerobic electron transfer flavoprotein (ETF) assay .

HY-CE00930

2E-Hexadecenoyl-CoA 2E-Hexadecenoyl-coenzyme A; trans-2-Hexadecenoyl-CoA; trans-2-Hexadecenoyl-S-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2E-Hexadecenoyl-CoA (2E-Hexadecenoyl-coenzyme A) is a 2-enoyl-CoA and a long-chain fatty acyl-CoA.

HY-CE00395

(S)-3-Hydroxyhexacosanoyl-CoA (S)-3-Hydroxyhexacosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(S)-3-Hydroxyhexacosanoyl-CoA ((S)-3-Hydroxyhexacosanoyl-coenzyme A) is a very long-chain hydroxy fatty acyl-CoA.

HY-CE00409

(S)-3-Hydroxypalmitoyl-CoA (S)-3-Hydroxypalmitoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(S)-3-Hydroxypalmitoyl-CoA ((S)-3-Hydroxypalmitoyl-coenzyme A) is a long-chain (3S)-hydroxy fatty acyl-CoA.

HY-E70254

Tricosanoyl-CoA triammonium	Others	Others
Tricosanoyl-CoA triammonium is a very long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A (HY-128851) with the carboxy group of tricosanoic acid (HY-W009081). Tricosanoyl-CoA is functionally related to a tricosanoic acid. Tricosanoyl-CoA is a conjugate acid of a tricosanoyl-CoA(4-).

HY-CE00438

(3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-CoA (3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-CoA ((3S,8Z,11Z,14Z,17Z)-3-Hydroxyicosatetraenoyl-coenzyme A) is a long-chain fatty acyl-CoA.

HY-CE00003

(15Z)-Tetracosenoyl-CoA Nervonoyl-coenzyme A	Biochemical Assay Reagents	Others
(15Z)-Tetracosenoyl-CoA (Nervonoyl-coenzyme A) is a long-chain fatty acyl-CoA.

HY-CE00049

(17Z)-Hexacosenoyl-CoA Ximenoyl-coenzyme A	Biochemical Assay Reagents	Others
(17Z)-Hexacosenoyl-CoA (Ximenoyl-coenzyme A) is a long-chain fatty acyl-CoA.

HY-B2246R

L-Carnitine hydrochloride (Standard) (R)-Carnitine hydrochloride (Standard); Levocarnitine hydrochloride (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
L-Carnitine (hydrochloride) (Standard) is the analytical standard of L-Carnitine (hydrochloride). This product is intended for research and analytical applications. L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B0399G

L-Carnitine (R)-Carnitine; Levocarnitine	Endogenous Metabolite	Neurological Disease Cancer
L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-W105518R

L-Carnitine tartrate (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease
L-Carnitine (tartrate) (Standard) is the analytical standard of L-Carnitine (tartrate). This product is intended for research and analytical applications. L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

HY-113166R

Dodecanoylcarnitine (Standard) (-)-Lauroylcarnitine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine (HY-113166). This product is intended for research and analytical applications. Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

HY-CE00307

(E)-2,3-Didehydropristanoyl-CoA trans-2,3-Dehydropristanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(E)-2,3-Didehydropristanoyl-CoA (trans-2,3-Dehydropristanoyl-coenzyme A) is a long-chain fatty acyl-CoA.

HY-CE00191A

(2E,13Z)-Icosadienoyl-CoA (2E,13Z)-Icosadienoyl-coenzyme A	Biochemical Assay Reagents	Others
(2E,13Z)-Icosadienoyl-CoA ((2E,13Z)-Icosadienoyl-coenzyme A) is a long-chain fatty acyl-CoA.

HY-CE00333

(3S,5Z)-3-Hydroxytetradec-5-enoyl-CoA (3S,5Z)-3-Hydroxytetradec-5-enoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(3S,5Z)-3-Hydroxytetradec-5-enoyl-CoA ((3S,5Z)-3-Hydroxytetradec-5-enoyl-coenzyme A) is a long-chain (3S)-hydroxy fatty acyl-CoA.

HY-176894

Hemiacetylcarnitinium chloride	Carnitine Palmitoyltransferase (CPT) Others	Metabolic Disease
Hemiacetylcarnitinium chloride is a inhibitor of fatty acid metabolism, specifically targeting carnitine palmitoyltransferase I (CPT I). Hemiacetylcarnitinium chloride disrupts the conversion of fatty acyl-CoA to fatty acyl carnitine, thereby blocking the subsequent oxidation of long-chain fatty acids and reducing the production of ATP required for energy-dependent cellular processes. Hemiacetylcarnitinium chloride can be used for the study of fatty acid metabolism .

HY-107396R

YM-750 (Standard)	Reference Standards Acyltransferase	Cardiovascular Disease
YM-750 (Standard) is the analytical standard of YM-750 (HY-107396). This product is intended for research and analytical applications. YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC₅₀=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .

HY-P2832B

Acyl-coenzyme A Synthetase, Pseudomonas sp.	Endogenous Metabolite	Metabolic Disease
Acyl-coenzyme A Synthetase, Pseudomonas sp. (EC 6.2.1.3) belongs to the ligase family and can activate the breakdown of complex fatty acids. Acyl-coenzyme A Synthetase, Pseudomonas sp. (EC 6.2.1.3) catalyzes the production of fatty acyl-CoA in a two-step process via an adenylate intermediate. Acyl-coenzyme A Synthetase, Pseudomonas sp. (EC 6.2.1.3) catalyzes the pre-reaction of fatty acid β-oxidation and can also be incorporated into phospholipids. Acyl-coenzyme A Synthetase, Pseudomonas sp. (EC 6.2.1.3) protein is involved in regulating and promoting the transport of long-chain fatty acids in mammalian cells.

HY-W754236

(R)-Carnitine Hydrochloride-13C3	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
(R)-Carnitine Hydrochloride- ¹³C₃ is the ¹³C-labeled L-Carnitine hydrochloride (HY-B2246). L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

Cat. No.	Product Name	Type

HY-B0399G

L-Carnitine (R)-Carnitine; Levocarnitine	Fluorescent Dyes
L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

L-Carnitine

(R)-Carnitine; Levocarnitine

Fluorescent Dyes

L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

Cat. No.	Product Name	Type

HY-W105518

L-Carnitine tartrate 15+ Cited Publications	Biochemical Assay Reagents
L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

L-Carnitine tartrate

15+ Cited Publications

Biochemical Assay Reagents

L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

HY-131303

Heptadecanoyl Coenzyme A Heptadecanoyl-CoA	Biochemical Assay Reagents
Heptadecanoyl Coenzyme A (Heptadecanoyl-CoA), long-chain acyl-coenzymes A (acyl-CoAs) (LCACoA), is an intermediate in lipid metabolism. Heptadecanoyl Coenzyme A can be used for the research of glucose metabolism .

HY-B0399G

L-Carnitine (R)-Carnitine; Levocarnitine	Biochemical Assay Reagents
L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

L-Carnitine

(R)-Carnitine; Levocarnitine

Biochemical Assay Reagents

HY-W105518R

L-Carnitine tartrate (Standard)	Biochemical Assay Reagents
L-Carnitine (tartrate) (Standard) is the analytical standard of L-Carnitine (tartrate). This product is intended for research and analytical applications. L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

L-Carnitine tartrate (Standard)

Biochemical Assay Reagents

L-Carnitine (tartrate) (Standard) is the analytical standard of L-Carnitine (tartrate). This product is intended for research and analytical applications. L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0399

L-Carnitine Maximum Cited Publications 20 Publications Verification (R)-Carnitine; Levocarnitine	Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Neurological Disease Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer Source Classification	Endogenous Metabolite
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-N6707

Triacsin C 5+ Cited Publications WS 1228A; FR 900190	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	ACSL Family Parasite
Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

HY-B2246

L-Carnitine hydrochloride Maximum Cited Publications 20 Publications Verification (R)-Carnitine hydrochloride; Levocarnitine hydrochloride	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-113201

Tetradecanoylcarnitine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Tetradecanoylcarnitine is an acylcarnitine involved in mitochondrial β-oxidation of long-chain saturated fatty acids and fatty acid metabolism. Tetradecanoylcarnitine serves as a biomarker for *very long-chain* acyl-CoA dehydrogenase** deficiency and MPTP (HY-15608)-induced Parkinson's disease. Tetradecanoylcarnitine exhibits a characteristic significant elevation in plasma levels in patients with sarcopenia, including those complicated with hypertension, and this elevation is closely associated with an increased risk of death. Tetradecanoylcarnitine is widely used in research on the pathological mechanisms of diseases such as Parkinson's disease and sarcopenia .

HY-B0399R

L-Carnitine (Standard) (R)-Carnitine (Standard); Levocarnitine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cancer Source Classification	Reference Standards Endogenous Metabolite
L-Carnitine (Standard) is the analytical standard of L-Carnitine. This product is intended for research and analytical applications. L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-W612338

9-Oxononanoic acid 9-ONA	Structural Classification Arachis hypogaea L. Leguminosae Ketones, Aldehydes, Acids Plants Source Classification	Acetyl-CoA Carboxylase
9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis .

HY-B2246R

L-Carnitine hydrochloride (Standard) (R)-Carnitine hydrochloride (Standard); Levocarnitine hydrochloride (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Carnitine (hydrochloride) (Standard) is the analytical standard of L-Carnitine (hydrochloride). This product is intended for research and analytical applications. L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-113166R

Dodecanoylcarnitine (Standard) (-)-Lauroylcarnitine (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine (HY-113166). This product is intended for research and analytical applications. Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704210

	ACSL1 Protein, Human (His) acyl-CoA synthetase 1; ACS1; Arachidonate--CoA ligase; long-chain acyl-CoA synthetase 1; LACS 1; long-chain acyl-CoA synthetase 2; LACS 2; long-chain fatty acid-CoA ligase 2; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; Phytanate--CoA ligase	Human	E. coli
	ACSL1 Protein, Human (His) is the recombinant human-derived ACSL1 protein, expressed by E. coli, with C-6*His tag.

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Cat. No.	Product Name	Chemical Structure

HY-B2246S

L-Carnitine-d9 chloride

1 Publications Verification

L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B0399S

L-Carnitine-d9

1 Publications Verification

L-Carnitine-d₉ is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B0399S2

L-Carnitine-13C3

L-Carnitine- ¹³C₃ ((R)-Carnitine- ¹³C₃) is the ¹³C--labeled L-Carnitine (HY-B0399). L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-W754236

(R)-Carnitine Hydrochloride-13C3

(R)-Carnitine Hydrochloride- ¹³C₃ is the ¹³C-labeled L-Carnitine hydrochloride (HY-B2246). L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

Host:	Mouse (3) Rabbit (2)
Reactivity:	Human (5) Rat (3) Mouse (3)
Application:	IHC-P (5) ICC/IF (2) IF-Tissue (1) IP (2) WB (5) ELISA (1)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (5) Recombinant (3)
Modification:	Unmodified (5)

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HY-P86465

	FACL4 Antibody (YA6157) long-chain-fatty-acid--CoA ligase 4; long-chain acyl-CoA synthetase 4; LACS 4; ACS4 antibody; ACSL 4 antibody; Acsl4 antibody	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	FACL4 Antibody (YA6157) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FACL4.

HY-P86761

	ACADVL/VLCAD Antibody (YA6454) ACAD 6 antibody; ACAD6 antibody; ACADV_HUMAN antibody; Acadvl antibody; acyl CoA dehydrogenase very long chain antibody; acyl Coenzyme A dehydrogenase very long chain antibody; LCACD antibody; mitochondrial antibody; Very long chain specific acyl CoA dehydrogenase antibody; Very long chain specific acyl CoA dehydrogenase mitochondrial antibody; ACAD 6 antibody; ACAD6 antibody; ACADV_HUMAN antibody; Acadvl antibody; acyl CoA dehydrogenase very long chain antibody; acyl Coenzyme A dehydrogenase very long chain antibody; LCACD antibody; mitochondrial antibody; Very long chain specific acyl CoA dehydrogenase antibody; Very long chain specific acyl CoA dehydrogenase mitochondrial antibody; Very long-chain specific acyl-CoA dehydrogenase antibody; VLCAD antibody;	WB, IHC-P, ICC/IF, IF-Tissue, IP	Human
	ACADVL/VLCAD Antibody (YA6454) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACADVL/VLCAD.

HY-P86762

	ACSL3 Antibody (YA6455) ACS3 antibody; Acsl3 antibody; ACSL3_HUMAN antibody; acyl CoA synthetase long chain family member 3 antibody; FACL3 antibody; Fatty acid Coenzyme A ligase long chain 3 antibody; LACS 3 antibody; LACS3 antibody; Lignoceroyl CoA synthase antibody; long chain acyl CoA synthetase 3 antibody; ACS3 antibody; Acsl3 antibody; ACSL3_HUMAN antibody; acyl CoA synthetase long chain family member 3 antibody; FACL3 antibody; Fatty acid Coenzyme A ligase long chain 3 antibody; LACS 3 antibody; LACS3 antibody; Lignoceroyl CoA synthase antibody; long chain acyl CoA synthetase 3 antibody; long chain fatty acid CoA ligase 3 antibody; long-chain acyl-CoA synthetase 3 antibody; long-chain-fatty-acid--CoA ligase 3 antibody; PRO2194 antibody;	WB, IHC-P	Human
	ACSL3 Antibody (YA6455) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACSL3.

HY-P87353

	ACSL1 Antibody (YA7036) ACS 1 antibody; ACS1 antibody; ACSL 1 antibody; ACSL1 antibody; ACSL1_HUMAN antibody; acyl CoA synthetase 1 antibody; acyl CoA synthetase long chain family member 1 antibody; acyl-CoA synthetase 1 antibody; FACL 1 antibody; FACL 2 antibody	WB, IHC-P	Human, Mouse, Rat
	ACSL1 Antibody (YA7036) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACSL1.

HY-P86763

	ACSL5 Antibody (YA6456) ACS2 antibody; ACS5 antibody; acyl CoA synthetase 5 antibody; acyl CoA synthetase long chain family member 5 antibody; EC 6.2.1.3 antibody; FACL5 antibody; FACL5 for fatty acid coenzyme A ligase 5 antibody; Fatty acid CoA ligase, long chain 5 antibody; Fatty acid coenzyme A ligase 5 antibody; Fatty acid Coenzyme A ligase long chain 5 antibody; ACS2 antibody; ACS5 antibody; acyl CoA synthetase 5 antibody; acyl CoA synthetase long chain family member 5 antibody; EC 6.2.1.3 antibody; FACL5 antibody; FACL5 for fatty acid coenzyme A ligase 5 antibody; Fatty acid CoA ligase, long chain 5 antibody; Fatty acid coenzyme A ligase 5 antibody; Fatty acid Coenzyme A ligase long chain 5 antibody; LACS 5 antibody; long chain acyl CoA synthetase 5 antibody; long chain fatty acid CoA ligase 5 antibody; long chain fatty acid coenzyme A ligase 5 antibody;	WB, IHC-P	Human, Mouse, Rat
	ACSL5 Antibody (YA6456) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ACSL5.

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Cat. No.	Product Name		Classification

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine		Cationic Lipids
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

Targets Recommended: ELOVL Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0399G

L-Carnitine (R)-Carnitine; Levocarnitine	Endogenous Metabolite	Neurological Disease Cancer
L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

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long-chain acyl-CoA

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