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nucleic acid monomers

" in MedChemExpress (MCE) Product Catalog:

40

Inhibitors & Agonists

1

Fluorescent Dyes

2

Biochemical Assay Reagents

23

Peptides

7

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148503
    5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

    		Phosphoramidites Nucleoside Antimetabolite/Analog Others
    5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer used to synthesize locked nucleic acid (LNA) analog oligonucleotides. It can be used as a building block of antisense oligonucleotides (ASOs) to target complementary RNA sequences. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) locks the furanose ring into an N-type conformation through 2',4'-constrained ethyl (cEt) modification, enhancing hybridization affinity and mismatch discrimination with RNA, while significantly improving the resistance of oligonucleotides to exonuclease digestion. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) mediates RNase H-dependent mRNA degradation or inhibits translation by forming a stable hybrid with RNA, thereby achieving gene expression regulation. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is mainly used in the development of antisense drugs, gene function research and oligonucleotide synthesis related to disease treatment .
    5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
  • HY-21242
    MMT-hexylaminolinker phosphoramidite

    		Drug Intermediate Phosphoramidites Others
    MMT-Hexylaminolinker Phosphoramidite is a degradable linker and aminoalkylphosphoramidite monomer that can be used for the synthesis of oligonucleotide gap sequences or other nucleic acid molecules .
    MMT-hexylaminolinker phosphoramidite
  • HY-W115727D
    Polyacrylamide,average Mn 40000

    PAM,average Mn 40000

    		 Biochemical Assay Reagents Others
    Polyacrylamide (PAM), average Mn 40000 is a versatile, high-molecular-weight polyacrylamide copolymer. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, act as drug carriers to achieve controlled release, serve as smart materials responding to temperature/pH stimuli, and be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .
    Polyacrylamide,average Mn 40000
  • HY-P2820
    Phosphoglucomutase, Rabbit muscle

    		Endogenous Metabolite Metabolic Disease
    Phosphoglucomutase, Rabbit muscle is often used in biochemical studies. Phosphoglucomutase is an enzyme that can transfer the phosphate group on the α-D-glucose monomer forward from the 1-position to the 6-position or reversely transfer from the 6-position to the 1-position, and promote the glucose-1-phosphate and glucose-6-phosphate Transform each other. Phosphoglucomutase is a key enzyme in glycolysis and gluconeogenesis, and plays an important role in the metabolism of proteins, lipids and nucleic acids .
    Phosphoglucomutase, Rabbit muscle
  • HY-164583
    DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite

    		Phosphoramidites DNA/RNA Synthesis Others
    DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite allows site-specific introduction of a 2'-O-C22 lipophilic modification at adenosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules .
    DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite
  • HY-W006103
    I-bu-rG Phosphoramidite

    		Phosphoramidites Drug Intermediate Others
    I-bu-rG Phosphoramidite is a phosphoramidite monomer that can be used in the synthesis of nucleotides and nucleic acids .
    I-bu-rG Phosphoramidite
  • HY-164582
    DMTr-2'-O-C22-rC(Ac)-3'-CE-Phosphoramidite

    		Phosphoramidites DNA/RNA Synthesis Others
    DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite enables site-specific introduction of 2'-O-C22 lipophilic modification at cytidine positions during oligonucleotide synthesis, which is used to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. Construction and mechanism study of DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite nucleic acid silencing molecules .
    DMTr-2'-O-C22-rC(Ac)-3'-CE-Phosphoramidite
  • HY-171631
    5'-O-DMTr-Nap-dU-3'-CE Phosphoramidite

    		DNA/RNA Synthesis Others
    5'-O-DMTr-Nap-dU-3'-CE Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
    5'-O-DMTr-Nap-dU-3'-CE Phosphoramidite
  • HY-21286
    N2-Isobutyryl-2'-O-methylguanosine

    		Drug Intermediate Others
    N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms .
    N2-Isobutyryl-2'-O-methylguanosine
  • HY-164581
    DMTr-2'-O-C22-rG(ibu)-3'-CE-Phosphoramidite

    		Phosphoramidites DNA/RNA Synthesis Others
    DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer for oligonucleotide synthesis. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite enables site-specific introduction of 2'-O-C22 lipophilic modification at guanosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipid solubility and tissue uptake efficiency of dsRNA. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules .
    DMTr-2'-O-C22-rG(ibu)-3'-CE-Phosphoramidite
  • HY-W540122
    Fmoc-PNA-C(Bhoc)-OH

    		Biochemical Assay Reagents Others
    Fmoc-PNA-C(Bhoc)-OH is a peptide nucleic acid monomers, and can be used in the synthesis of peptide nucleic acid compounds .
    Fmoc-PNA-C(Bhoc)-OH
  • HY-W881217
    DMT-iBu-G-(S)-GNA Phosphoramidite

    		DNA/RNA Synthesis Others
    DMT-iBu-G-(S)-GNA Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
    DMT-iBu-G-(S)-GNA Phosphoramidite
  • HY-403188
    5'(E)-VP-2'-OMe-Bz-C Phosphoramidite

    		DNA/RNA Synthesis Others
    5'(E)-VP-2'-OMe-Bz-C Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
    5'(E)-VP-2'-OMe-Bz-C Phosphoramidite
  • HY-W784611
    3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite

    		DNA/RNA Synthesis Others
    3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
    3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite
  • HY-W320685
    (S)-N-Boc-L-homoserine ethyl ester

    		Drug Intermediate Others
    (S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.
    (S)-N-Boc-L-homoserine ethyl ester
  • HY-W784625
    Boc-PNA-G(Z)-OH

    		Drug Intermediate Others
    Boc-PNA-G(Z)-OH is a peptide nucleic acid (PNA) monomer that is used for the synthesis of peptide nucleic acid oligomers .
    Boc-PNA-G(Z)-OH
  • HY-P11687
    Fmoc-PNA-M(Boc)-OH

    		Drug Intermediate Others
    Fmoc-PNA-M(Boc)-OH is a peptide nucleic acid monomer with Fmoc and Boc protecting groups. Fmoc-PNA-M(Boc)-OH can be used for synthesis of peptide nucleic acid .
    Fmoc-PNA-M(Boc)-OH
  • HY-W784624
    Boc-PNA-C(Z)-OH

    		Drug Intermediate Others
    Boc‑PNA‑C (Z)‑OH is a cytosine-containing peptide nucleic acid monomer, in which the amino group and cytosine are protected by tert-butoxycarbonyl (Boc) and benzyloxycarbonyl groups, respectively. Boc‑PNA‑C (Z)‑OH can be used for the synthesis of peptide nucleic acids .
    Boc-PNA-C(Z)-OH
  • HY-W784623
    Boc-PNA-A(Z)-OH

    		Drug Intermediate Others
    Boc-PNA-A(Z)-OH is a Boc-protected peptide nucleic acid monomer with a benzyloxycarbonyl protecting group on the adenine base .
    Boc-PNA-A(Z)-OH
  • HY-W402665
    Fmoc-PNA-T-OH

    Fmoc-C(Bhoc)-Aeg-OH

    		 Drug Intermediate Metabolic Disease
    Fmoc-PNA-T-OH (Fmoc-C (Bhoc)-Aeg-OH) is a Bhoc-protected peptide nucleic acid (PNA) monomer. Fmoc-PNA-T-OH is used in the research of type 2 diabetes (t2d) .
    Fmoc-PNA-T-OH
  • HY-W665456
    Fmoc-PNA-U-OH

    		Drug Intermediate Others
    Fmoc‑PNA‑U‑OH is a peptide nucleic acid monomer that can be used for the synthesis of peptide nucleic acids (PNAs). Fmoc‑PNA‑U‑OH exhibits specific binding to adenine, resistance to enzymatic degradation, and strong hybridization properties. Fmoc‑PNA‑U‑OH can be applied in research fields such as gene diagnosis, molecular biology, and antisense therapy.
    Fmoc-PNA-U-OH
  • HY-W574398
    Fmoc-Aeg-OH

    		Biochemical Assay Reagents Others
    Fmoc-Aeg-OH is a peptide nucleic acid (PNA) backbone intermediate and an Fmoc-protected carboxylic acid. Fmoc-Aeg-OH can be coupled with base acetic acids to synthesize Fmoc-protected PNA monomers, including those with modified bases .
    Fmoc-Aeg-OH
  • HY-W784626
    Boc-PNA-T-OH

    		Drug Intermediate Others
    Boc-PNA-T-OH is a thymine-containing peptide nucleic acid monomer and solid-phase synthesis building block .
    Boc-PNA-T-OH
  • HY-P11691
    Fmoc-PNA-D(tetraBoc)-OH

    		Biochemical Assay Reagents Others
    Fmoc-PNA-D (tetraBoc)-OH is an Fmoc/Boc-protected diaminopurine peptide nucleic acid (PNA) monomer suitable for standard Fmoc solid-phase synthesis. Fmoc-PNA-D (tetraBoc)-OH carries Boc-protected exocyclic amino groups and can be incorporated into pseudo-complementary PNA oligomers for applications in antigenic peptide nucleic acid and DNA nanotechnology research .
    Fmoc-PNA-D(tetraBoc)-OH
  • HY-W540123
    Fmoc-PNA-A(Bhoc)-OH

    		Biochemical Assay Reagents Cancer
    Fmoc-PNA-A(Bhoc)-OH is a protected peptide nucleic acid (PNA) monomer carrying an adenine base. Fmoc-PNA-A(Bhoc)-OH contains Fmoc and benzhydryloxycarbonyl (Bhoc) protecting groups, and serves as a standard building block designed specifically for solid-phase PNA synthesis. Fmoc-PNA-A(Bhoc)-OH can be efficiently used to synthesize PNA-based sequence-specific hybridization probes. These probes have broad applications in molecular biology research; for example, they can be used in HER2-expressing tumor-related studies, providing tools for disease diagnosis and mechanism exploration .
    Fmoc-PNA-A(Bhoc)-OH
  • HY-W1008618
    (R)-GNA-C(Bz)-phosphoramidite

    		Biochemical Assay Reagents Others
    (R)-GNA-C(Bz)-phosphoramidite is a monomer that can be used to make special glycol nucleic acid (GNA) oligonucleotides.
    (R)-GNA-C(Bz)-phosphoramidite
  • HY-P11696
    H-Aeg(Fmoc)-OH hydrochloride

    		Drug Intermediate Others
    H-Aeg(Fmoc)-OH hydrochloride is an Fmoc-protected aminoethylglycine monomer with a free carboxyl group and can be used for peptide nucleic acid synthesis.
    H-Aeg(Fmoc)-OH hydrochloride
  • HY-W025936
    Fmoc-PNA-G(Bhoc)-OH

    		Drug Intermediate Others
    Fmoc‑PNA‑G (Bhoc)‑OH is a guanine-containing peptide nucleic acid monomer, in which both Bhoc on the nucleobase and Fmoc on the backbone serve as protecting groups. Fmoc‑PNA‑G (Bhoc)‑OH is applicable for the synthesis of peptide nucleic acids .
    Fmoc-PNA-G(Bhoc)-OH
  • HY-P11689
    Fmoc-PNA-J(Bhoc)-OH

    		Biochemical Assay Reagents Others
    Fmoc-PNA-J (Bhoc)-OH is a protected peptide nucleic acid (PNA) monomer building block used for solid-phase synthesis of PNA oligomers. Fmoc-PNA-J (Bhoc)-OH carries Fmoc/Bhoc protecting groups and functions as a standard Fmoc-protected PNA monomer .
    Fmoc-PNA-J(Bhoc)-OH
  • HY-P11697
    Fmoc-PNA-maleimide-OH

    		Drug Intermediate Others
    Fmoc-PNA-maleimide-OH is a Fmoc-protected functionalized peptide nucleic acid monomer featuring a maleimide group for thiol-reactive conjugation. Fmoc-PNA-maleimide-OH can be used in constructing PNA conjugates for molecular assembly applications.
    Fmoc-PNA-maleimide-OH
  • HY-D3405
    BO-TAP-3

    		Fluorescent Dye Others
    BO-TAP-3 is an orange fluorescent carbocyanine monomer dye, and it is also a cell impermeable nucleic acid staining agent. When there is no nucleic acid present, BO-TAP-3 shows a non-fluorescent state. However, when it binds to double-stranded DNA, it exhibits multiple fluorescence enhancement effects. BO-TAP-3 can be used for cell nucleus and cytoplasm imaging, bacterial and sperm labeling, and can also be applied in nucleic acid detection and amplification research. It can also be used as a temperature sensor (Ex/Em = 564/600 nM).
    BO-TAP-3
  • HY-P11679
    Boc-PNA-U-OH

    		DNA/RNA Synthesis Others
    Boc-PNA-U-OH is a protected peptide nucleic acid (PNA) monomer containing a uracil base, designed for solid-phase peptide synthesis (SPPS) using the Boc/Z protection strategy. Boc-PNA-U-OH acts as a building block in creating PNA oligomers that are neutral, stable, and used for antisense/antigene applications.
    Boc-PNA-U-OH
  • HY-P11682
    Boc-PNA-M(Z)-OH

    		DNA/RNA Synthesis Others
    Boc-PNA-M(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase peptide synthesis (SPPS). Boc-PNA-M(Z)-OH consists of an adenyl base protected with a benzyloxycarbonyl (Z) group and a backbone protected with a tert-butyloxycarbonyl (Boc) group, typically used for creating PNA oligomers.
    Boc-PNA-M(Z)-OH
  • HY-P11685
    Fmoc-PNA-thioU(PMB)-OH

    		DNA/RNA Synthesis Others
    Fmoc-PNA-thioU(PMB)-OH is a nucleobase-modified peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Fmoc-PNA-thioU(PMB)-OH features a thiouracil base protected with a p-methoxybenzyl (PMB) group on an Fmoc-protected backbone, designed for incorporating modified PNA bases into oligonucleotides to study binding properties.
    Fmoc-PNA-thioU(PMB)-OH
  • HY-P11695
    Fmoc-Aeg(Dde)

    		Biochemical Assay Reagents Others
    Fmoc-Aeg (Dde) is a protected aminoethylglycine (AEG) monomer used for solid-phase synthesis of peptide nucleic acids (PNAs). Fmoc-Aeg (Dde) contains the fluorenylmethoxycarbonyl (Fmoc) and 1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene) ethyl (Dde) protecting groups .
    Fmoc-Aeg(Dde)
  • HY-P11683
    Boc-PNA-D(tetraZ)-OH

    		DNA/RNA Synthesis Others
    Boc-PNA-D(tetraZ)-OH is a specialized Peptide Nucleic Acid (PNA) monomer used in solid-phase peptide synthesis, featuring a N-tert-butoxycarbonyl (Boc) protected backbone and a 2,6-diaminopurine nucleobase. Boc-PNA-D(tetraZ)-OH helps increase PNA solubility and binding affinity, often used in molecular diagnostics.
    Boc-PNA-D(tetraZ)-OH
  • HY-P11681
    Boc-PNA-J(Z)-OH

    		DNA/RNA Synthesis Others
    Boc-PNA-J(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Boc-PNA-J(Z)-OH features a 2,6-diaminopurine (J) base, protected by a carboxybenzyl (Z) group, attached to a Boc-protected aminoethylglycinate backbone. Boc-PNA-J(Z)-OH allows for the synthesis of PNA sequences with enhanced binding affinity and stability.
    Boc-PNA-J(Z)-OH
  • HY-P11684
    Fmoc-PNA-C(Boc)-OH

    		DNA/RNA Synthesis Others
    Fmoc-PNA-C(Boc)-OH is a protected peptide nucleic acid (PNA) monomer for solid-phase synthesis. Fmoc-PNA-C(Boc)-OH possesses Fmoc-protected skeletal amino groups and Boc-protected cytosine bases, designed to construct stable synthetic DNA analogs. Fmoc-PNA-C(Boc)-OH can be used to prepare highly specific, enzyme-stable antisense probes and diagnostic probes.
    Fmoc-PNA-C(Boc)-OH
  • HY-P11680
    Boc-PNA-thioU(PMB)-OH

    		DNA/RNA Synthesis Others
    BOC-PNA-thioU(PMB)-OH is a peptide nucleic acid (PNA) monomer characterized by a PMB protecting group on its thiouracil, which enhances its binding affinity to adenine. BOC-PNA-thioU(PMB)-OH exhibits excellent resistance to enzymatic degradation and strong hybridization properties, making it valuable for applications in gene diagnosis, antisense therapy, and other molecular biology fields requiring higher binding strength and greater functionalization.
    Boc-PNA-thioU(PMB)-OH
  • HY-P11688
    Fmoc-PNA-M(Bhoc)-OH

    		Biochemical Assay Reagents Others
    Fmoc-PNA-M (Bhoc)-OH is a standard peptide nucleic acid (PNA) monomer building block. Fmoc-PNA-M (Bhoc)-OH carries two protecting groups, Fmoc and Bhoc, and is specifically designed for solid-phase and automated PNA synthesis. Fmoc-PNA-M (Bhoc)-OH efficiently participates in the construction of sequence-specific PNA probes. Through its protecting group strategy, Fmoc-PNA-M (Bhoc)-OH ensures the accuracy and efficiency of PNA synthesis, and is one of the important raw materials for PNA synthesis at present .
    Fmoc-PNA-M(Bhoc)-OH

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