Fmoc-PNA-M(Bhoc)-OH
Fmoc-PNA-M (Bhoc)-OH is a standard peptide nucleic acid (PNA) monomer building block. Fmoc-PNA-M (Bhoc)-OH carries two protecting groups, Fmoc and Bhoc, and is specifically designed for solid-phase and automated PNA synthesis. Fmoc-PNA-M (Bhoc)-OH efficiently participates in the construction of sequence-specific PNA probes. Through its protecting group strategy, Fmoc-PNA-M (Bhoc)-OH ensures the accuracy and efficiency of PNA synthesis, and is one of the important raw materials for PNA synthesis at present.
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- Fòrmula: C40H36N4O7
- Peso molecular:684.74
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
Fmoc-PNA-M(Bhoc)-OH (2 μM; 25 °C) forms similar secondary structures with complementary DNA regardless of the monomer's position (middle, C-terminus, or both), while single-strand modified PNAs exhibit very low optical activity[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 684.74
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Fòrmula C40H36N4O7
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Petkowski JJ, et al. Astrobiological implications of the stability and reactivity of peptide nucleic acid (PNA) in concentrated sulfuric acid. Sci Adv. 2025;11(13):eadr0006. [Content Brief]
[2]. Polak A, et al. The Application of Peptide Nucleic Acids (PNA) in the Inhibition of Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Gene Expression in a Cell-Free Transcription/Translation System. Int J Mol Sci. 2024;25(3):1463. Published 2024 Jan 25. [Content Brief]
[3]. Pensato S, et al. gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions. Bioorg Chem. 2010;38(5):196-201. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fmoc-PNA-M(Bhoc)-OH Related Classifications
HY-P11688 Related Classifications
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