2. Others Anti-infection
  3. Isotope-Labeled Compounds Antibiotic Bacterial
  4. Sulfamethoxazole-13C6

Sulfamethoxazole-13C6  (Synonyms: Ro 4-2130-13C6)

製品番号: HY-B0322S1 純度: 99.91%
COA 取扱説明書 Technical Support

Sulfamethoxazole-13C6 (Ro 4-2130-13C6) is a 13C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.

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Sulfamethoxazole-<sup>13</sup>C<sub>6</sub>

Sulfamethoxazole-13C6 構造式

CAS 番号 : 1196157-90-0

容量 価格（税別） 在庫状況 数量
1 mg $200 在庫あり
5 mg $600 在庫あり
10 mg   お問い合わせ  
50 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Sulfamethoxazole-13C6 関連抗体

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製品説明

Sulfamethoxazole-13C6 (Ro 4-2130-13C6) is a 13C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfamethoxazole-13C6 関連抗体
分子量

259.23

分子式

C413C6H11N3O3S
CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=[S](NC1=NOC(C)=C1)([13C]([13CH]=[13CH]2)=[13CH][13CH]=[13C]2N)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外: 

DMSO : ≥ 100 mg/mL (385.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.1 mg/mL (0.39 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8576 mL 19.2879 mL 38.5758 mL
5 mM 0.7715 mL 3.8576 mL 7.7152 mL
10 mM 0.3858 mL 1.9288 mL 3.8576 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.91%

COA (233 KB) HNMR (118 KB) LCMS (88 KB) Elemental Analysis Report (108 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8576 mL 19.2879 mL 38.5758 mL 96.4395 mL
5 mM 0.7715 mL 3.8576 mL 7.7152 mL 19.2879 mL
10 mM 0.3858 mL 1.9288 mL 3.8576 mL 9.6439 mL
15 mM 0.2572 mL 1.2859 mL 2.5717 mL 6.4293 mL
20 mM 0.1929 mL 0.9644 mL 1.9288 mL 4.8220 mL
25 mM 0.1543 mL 0.7715 mL 1.5430 mL 3.8576 mL
30 mM 0.1286 mL 0.6429 mL 1.2859 mL 3.2146 mL
40 mM 0.0964 mL 0.4822 mL 0.9644 mL 2.4110 mL
50 mM 0.0772 mL 0.3858 mL 0.7715 mL 1.9288 mL
60 mM 0.0643 mL 0.3215 mL 0.6429 mL 1.6073 mL
80 mM 0.0482 mL 0.2411 mL 0.4822 mL 1.2055 mL
100 mM 0.0386 mL 0.1929 mL 0.3858 mL 0.9644 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Sulfamethoxazole-13C6 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfamethoxazole-13C61196157-90-0Ro 4-2130-13C6Isotope-Labeled CompoundsAntibioticBacterial13C labeledsulfonamide bacteriostatic antibioticbacterial infectionsPABAInhibitorinhibitorinhibit

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製品名:
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製品番号:
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