trans-Zeatin-d₅

Name: trans-Zeatin-d 5
Brand: MedChemExpress
SKU: HY-19700S
Rating: 4.5 (0 reviews)

製品番号: HY-19700S 純度: 99.2%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

trans-Zeatin-d₅ is deuterium labeled trans-Zeatin. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

trans-Zeatin-d₅ 構造式

CAS 番号 : 72963-19-0

容量	価格（税別）	在庫状況	数量
1 mg	$726	在庫あり	Estimated Time of Arrival: December 31
5 mg		お問い合わせ
10 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of trans-Zeatin-d₅:

trans-Zeatin 在庫あり

MEK アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

MEK1 MEK2 MEK5 MEK MAP2K4/MEK4 MAP2K7/MEK7

ERK アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

ERK ERK1 ERK2 ERK5 ERK8

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

224.27

分子式

C₁₀H₈D₅N₅O

CAS 番号

72963-19-0

Unlabeled CAS

1637-39-4

Appearance

Solid

Color

White to off-white

SMILES

OC([2H])([2H])/C(C([2H])([2H])[2H])=C/CNC1=C2C(N=CN2)=NC=N1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 25 mg/mL (111.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4589 mL	22.2946 mL	44.5891 mL
5 mM	0.8918 mL	4.4589 mL	8.9178 mL
10 mM	0.4459 mL	2.2295 mL	4.4589 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.2%

Select Batch:

データシート (273 KB) SDS (251 KB)

COA (249 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Li Q, et al. Endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey. Environ Sci Pollut Res Int. 2016 Dec;23(23):23422-23435. Epub 2016 Sep 9. [Content Brief]

[3]. Ji C, et al. Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int J Mol Med. 2010 Aug;26(2):257-63. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4589 mL	22.2946 mL	44.5891 mL	111.4728 mL
	5 mM	0.8918 mL	4.4589 mL	8.9178 mL	22.2946 mL
	10 mM	0.4459 mL	2.2295 mL	4.4589 mL	11.1473 mL
	15 mM	0.2973 mL	1.4863 mL	2.9726 mL	7.4315 mL
	20 mM	0.2229 mL	1.1147 mL	2.2295 mL	5.5736 mL
	25 mM	0.1784 mL	0.8918 mL	1.7836 mL	4.4589 mL
	30 mM	0.1486 mL	0.7432 mL	1.4863 mL	3.7158 mL
	40 mM	0.1115 mL	0.5574 mL	1.1147 mL	2.7868 mL
	50 mM	0.0892 mL	0.4459 mL	0.8918 mL	2.2295 mL
	60 mM	0.0743 mL	0.3716 mL	0.7432 mL	1.8579 mL
	80 mM	0.0557 mL	0.2787 mL	0.5574 mL	1.3934 mL
	100 mM	0.0446 mL	0.2229 mL	0.4459 mL	1.1147 mL