wkwkwNGwkwkw-NH2

Cat. No.: HY-P11468: Fiche technique Instruction de manipulation
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wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing.

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Synthèse de peptides personnalisée

wkwkwNGwkwkw-NH2 Chemical Structure

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Description	wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing^[1].
Masse moléculaire	1818.13
Formule	C₉₆H₁₂₀N₂₄O₁₃
Sequence	{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-Asn-Gly-{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-NH2
Sequence Shortening	{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-NG-{d-Trp}-{d-Lys}-{d-Trp}-{d-Lys}-{d-Trp}-NH2
Livraison	Room temperature in continental US; may vary elsewhere.
Stockage	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation	Fiche technique (259 KB) Instruction de manipulation (2659 KB)
Références	[1]. Li B, et al. Novel β-Hairpin Antimicrobial Peptide Containing the β-Turn Sequence of -NG- and the Tryptophan Zippers Facilitate Self-Assembly into Nanofibers, Exhibiting Excellent Antimicrobial Performance. J Med Chem. 2024 Apr 25;67(8):6365-6383. [Content Brief]