2. PROTAC Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis
  3. Ligands for Target Protein for PROTAC Reactive Oxygen Species (ROS) Apoptosis Caspase
  4. Zinc phthalocyanine

Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications.

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Zinc phthalocyanine

Zinc phthalocyanine 화학구조

CAS No. : 14320-04-8

사이즈 가격 재고 수량
500 mg 해외재고보유
1 g 해외재고보유
5 g 해외재고보유
10 g 해외재고보유
25 g 해외재고보유
50 g   견적 받기  

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Zinc phthalocyanine Related Antibodies

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제품 설명

Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications[1][2][3][4].

In Vitro

Zinc phthalocyanine (1-10 μM, 24 h) inhibits the growth of cancer cell Kyse-140 and OE-33 with IC50 of 1.41 μM and 3.35 μM[3].
Zinc phthalocyanine (1-10 μM, 24 h) is a photosensitizer that can be taken up by cancer cells and produces ROS under light irradiation of a specific wavelength (694 nm), impaires mitochondrial membrane integrity, activates caspase-3, and induces apoptosis[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Zinc phthalocyanine Related Antibodies

Cell Proliferation Assay[3]

Cell Line: Kyse-140 and OE-33
Concentration: 1-10 μM
Incubation Time: 24 h
Result: Inhibited cell proliferation under light irradiation.

Western Blot Analysis[3]

Cell Line: OE-33
Concentration: 1-10 μM
Incubation Time: 24 h
Result: Inhibited the expression of Bcl-2.
In Vivo

Zinc phthalocyanine (10 µM, topical application, single dose) causes long-term damage to the microvascular network of the CAM, exhibits antitumor activity in chick chorioallantoic membrane models[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Chick chorioallantoic membrane models[3]
Dosage: 10 µM
Administration: topical application, single dose
Result: Reduced tumor volume, destoryed the microvascular network.
분자량

577.90

화학식

C32H16N8Zn
CAS No.
Appearance

Solid

Color

Purplish red to black

Excitation (Ex)

620
SMILES

[N-]12[Zn+2]34[N-]5C6=NC(C7=CC=CC=C87)=[N]3C8=NC1=C(C=CC=C9)C9=C2N=C%10[N]4=C(C%11=CC=CC=C%10%11)N=C5C%12=CC=CC=C6%12
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

용액&용해도
In Vitro: 

DMF : < 1 mg/mL (insoluble)

*Zinc phthalocyanine is usually formulated as a suspension.

  • 몰농도 계산기

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 98.0%

SDS (393 KB)

COA (265 KB) HNMR (286 KB)

Handling Instructions (2659 KB)
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Zinc phthalocyanine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zinc phthalocyanine14320-04-8ZnPcLigands for Target Protein for PROTACReactive Oxygen Species (ROS)ApoptosisCaspaseTarget Protein-binding Moietycatalystsphotoconductorsphotodynamic therapyPDTsolar-cell applicationsInhibitorinhibitorinhibit

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상품명:
Zinc phthalocyanine
Cat. No.:
HY-19204
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SAFETY DATA SHEET (SDS)

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