2. Natural Products
  3. Alkaloids
  4. Indole Alkaloids

Indole Alkaloids

Indole Alkaloids (239):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15141
    Staurosporine 62996-74-1 99.98%
    Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer.
    Staurosporine
  • HY-A0190
    Ceruletide 17650-98-5 99.96%
    Ceruletide is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts.
    Ceruletide
  • HY-18569
    3-Indoleacetic acid 87-51-4 99.97%
    3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid
  • HY-N0737A
    Harmine 442-51-3 99.88%
    Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM.
    Harmine
  • HY-N0114
    Evodiamine 518-17-2 99.59%
    Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.
    Evodiamine
  • HY-N11803
    Arundanine 618852-71-4
    Arundanine is an dimeric alkaloid, which can be isolated from Arundo donax. .
    Arundanine
  • HY-N3098
    Pelirine 30435-26-8
    Pelirine is an alkaloid isolated from R. perakensis and causes death in mice at concentrations of 100 mg/kg and above.
    Pelirine
  • HY-N9713
    Dihydroxyaflavinine 76410-56-5
    Dihydroxyaflavinine (Compound Ⅲ) is an indole metabolite extracted from Aspergillus flavus.
    Dihydroxyaflavinine
  • HY-N0170
    Indole-3-carbinol 700-06-1 ≥98.0%
    Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
    Indole-3-carbinol
  • HY-N0480
    Reserpine 50-55-5 99.83%
    Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
    Reserpine
  • HY-N6732
    K-252a 99533-80-9 99.45%
    K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.
    K-252a
  • HY-12715
    Yohimbine 146-48-5 99.91%
    Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.
    Yohimbine
  • HY-N0117
    Indirubin 479-41-4 98.74%
    Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia.
    Indirubin
  • HY-N2143
    Fumitremorgin C 118974-02-0 99.20%
    Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor.
    Fumitremorgin C
  • HY-N0127
    Yohimbine Hydrochloride 65-19-0 99.89%
    Yohimbine Hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.
    Yohimbine Hydrochloride
  • HY-N7131
    Coumarin 6 38215-36-0 99.93%
    Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm).
    Coumarin 6
  • HY-N0166
    Gramine 87-52-5 99.63%
    Gramine (Donaxine) is a natural alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine (Donaxine) has anti-tumor, anti-viral and anti-inflammatory properties.
    Gramine
  • HY-N2022
    Castanospermine 79831-76-8 ≥98.0%
    Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).
    Castanospermine
  • HY-119502
    Camalexin 135531-86-1 99.44%
    Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production.
    Camalexin
  • HY-13295
    Vinpocetine 42971-09-5 99.57%
    Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders.
    Vinpocetine