2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7543
    Schisantherin D 64917-82-4 99.66%
    Schisantherin D is a lignan. Schisantherin D can be isolated from Kadsura interior. Schisantherin D downregulates the expression of ETBR and inhibits the secretion of ECM and ET-1. Schisantherin D alleviates EtOH + ET-1-induced hepatocyte cytotoxicity. Schisantherin D potently inhibits HIV replication in cells.
    Schisantherin D
  • HY-N7906
    Myricetin 3-O-glucoside 19833-12-6 99.87%
    Myricetin 3-O-glucoside (Myricetin 3-β-D-glucopyranoside) is a flavonol from Tibouchina paratropica and Hakmeitau beans. Myricetin 3-O-glucoside exhibits anti-Leishmanial, anti-inflammatory and antimicrobial activities.
    Myricetin 3-O-glucoside
  • HY-N9343
    Kulactone 22611-36-5 98.0%
    Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB).
    Kulactone
  • HY-N9357
    Granilin 40737-97-1 99.60%
    Granilin, a sesquiterpene lactone, can be found in the flower buds of Carpesium triste. Granilin can be used as the bactericide and fungicide.
    Granilin
  • HY-P2717
    Ac-YVAD-AMC 149231-65-2 99.64%
    Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells.
    Ac-YVAD-AMC
  • HY-P2822
    Phosphoglycerate kinase, yeast 9001-83-6
    Phosphoglycerate kinase (PGK), yeast is a monomeric glycolytic/gluconeogenic enzyme that can be found in Saccharomyces cerevisiae. Phosphoglycerate kinase, yeast catalyzes phosphoryl-group transfer from 1,3-bisphosphoglycerate to ADP to form 3-phosphoglycerate and ATP, binds 3PGA, ATP, and Mg2+, and adopts a closed conformation. Phosphoglycerate kinase, yeast is commonly used in biochemical research.
    Phosphoglycerate kinase, yeast
  • HY-P2866
    β-N-Acetylhexosaminidase, Streptococcus pneumoniae 9012-33-3
    β-N-Acetylhexosaminidase, Streptococcus pneumoniae is a cell surface virulence factor of Streptococcus pneumoniae, which contains two synergistically acting GH20 domains (with higher activity in GH20-2). β-N-Acetylhexosaminidase, Streptococcus pneumoniae specifically recognizes and hydrolyzes substrates with β(1,2) glycosidic bonds via Trp-443 and Tyr-482 residues. β-N-Acetylhexosaminidase, Streptococcus pneumoniae catalyzes the hydrolysis of β(1,2)-linked N-acetylglucosamine groups and related disaccharides, and promotes persistent colonization of bacteria in the airway by modifying host defense molecules and releasing monosaccharides for bacterial growth. β-N-Acetylhexosaminidase, Streptococcus pneumoniae can be used in studies related to Streptococcus pneumoniae infection, acute pneumonia, otitis media and meningitis.
    β-N-Acetylhexosaminidase, Streptococcus pneumoniae
  • HY-P3512
    Iseganan 257277-05-7 98.87%
    Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research.
    Iseganan
  • HY-100358
    AQ-13 dihydrochloride 169815-40-1 98.08%
    AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum.
    AQ-13 dihydrochloride
  • HY-101011
    Naloxonazine dihydrochloride 880759-65-9
    Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC50 of 5.4 nM. Naloxonazine dihydrochloride also shows anti-leishmanial activity.
    Naloxonazine dihydrochloride
  • HY-101479
    Iclaprim 192314-93-5 98.92%
    Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
    Iclaprim
  • HY-101725
    Meclonazepam 58662-84-3 99.97%
    Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect. Meclonazepam is active against immature S. mansoni. Meclonazepam (30 μM) eliminates 100% of immature parasites. Meclonazepam has a anti-schistosomal effect.
    Meclonazepam
  • HY-106755
    Tucaresol 84290-27-7
    Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti-HIV effect.
    Tucaresol
  • HY-107566
    Conessine 546-06-5 99.87%
    Conessine is an orally active and BBB-penetrable selective histamine H3 receptor antagonist. The pKi values of Conessine for rat and human H3 receptors are 7.61 and 8.27, respectively. Conessine is an inhibitor of the multidrug efflux pump system in Pseudomonas aeruginosa and can enhance the activity of antibiotics. Conessine has antimalarial activity. Conessine can also be used in the research of muscle atrophy.
    Conessine
  • HY-107577
    Gedunin 2753-30-2 ≥98.0%
    Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research.
    Gedunin
  • HY-107789
    Sodium lauryl sulfoacetate 1847-58-1 98.0%
    Sodium lauryl sulfoacetate is a solid anionic surfactant of plant origin. Sodium lauryl sulfoacetate is an immunoadjuvant with antiimmunosuppressive effects. Sodium lauryl sulfoacetate has antiviral activity.
    Sodium lauryl sulfoacetate
  • HY-110248
    MI 14 1715934-43-2 99.30%
    MI 14 is a selective PI4KIIIβ inhibitor with IC50s of 54 nM, >100 μM, >100 μM for PI4KIIIβ, PI4KIIIα, PI4KIIα, respectively. MI 14 has antiviral activity against HCV 1b, CVB3, HRVM, HVC 2a.
    MI 14
  • HY-111521
    Meropenem-vaborbactam 2031124-72-6
    Meropenem-vaborbactam (Carbavance) is a Carbapenem Antibiotic and Boronic acid-based beta-lactamase inhibitor, is a fixed-dose combination product with potent in vitro activity against Enterobacteriaceae that are Klebsiella pneumoniae carbapenemase producers. Meropenem-vaborbactam exhibits activity against Pseudomonas aeruginosa isolates , with an MIC50 of 0.5 μg/mL and an MIC90 of 8 μg/mL.
    Meropenem-vaborbactam
  • HY-112665
    Virginiamycin Complex 11006-76-1
    Virginiamycin Complex (Streptogramin) is an antibiotic containing two streptogramins, virginiamycin M (VM) and virginiamycin S (VS), which are produced by S. virginiae. As a complex, these two antibiotics in Virginiamycin Complex act synergistically. The action of VM is persistent and catalytic, and it can alter the affinity of ribosomes for VS. Virginiamycin Complex irreversibly inhibits protein synthesis in bacteria and has antibacterial activity.
    Virginiamycin Complex
  • HY-112832
    Lumigen APS-5 193884-53-6 98.0%
    Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP).
    Lumigen APS-5
Cat. No. Product Name / Synonyms Application Reactivity