CDK7 Inhibitor

CDK7 Inhibitors (71):

Cat. No.	Product Name	Effect	Purity

HY-16297A

Abemaciclib	Inhibitor	99.83%
Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC₅₀ values of 2 nM and 10 nM for CDK4 and CDK6, respectively.

HY-16297

Abemaciclib methanesulfonate	Inhibitor	99.95%
Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC₅₀s of 2 nM and 10 nM for CDK4 and CDK6, respectively.

HY-103618

THZ531	Inhibitor	99.86%
THZ531 is a selective and covalent inhibitor of both CDK12 and CDK13 with IC₅₀s of 158 nM and 69 nM, respectively.

HY-80013

THZ1	Inhibitor	99.84%
THZ1 is a selective and potent covalent CDK7 inhibitor with an IC₅₀ of 3.2 nM.

HY-10008

SNS-032	Inhibitor	99.49%
SNS-032 (BMS-387032) is a potent and selective inhibitor of CDK2, CDK7, and CDK9 with IC₅₀s of 38 nM, 62 nM and 4 nM, respectively.

HY-151898

CDK4/6-IN-14

CDK4/6-IN-14 is a potent and highly selective CDK4 and CDK6 (HY-151878

CDK7-IN-20 is a potent, selective and irreversible CDK7 (HY-138293

SY-5609

Inhibitor 99.66%

SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a K_D of 0.065 nM.

HY-50940

AT7519

Inhibitor 99.76%

AT7519 (AT7519M) as a potent inhibitor of CDKs, with IC₅₀s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively.

HY-101257

YKL-5-124

Inhibitor 98.03%

YKL-5-124 is a potent, selective, irreversible and covalent CDK7 inhibitor with IC₅₀s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively.

HY-80013A

THZ1 Hydrochloride

Inhibitor 98.78%

THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC₅₀ of 3.2 nM.

HY-13914

Roniciclib

Inhibitor 98.03%

Roniciclib is an orally bioavailable pan-cyclin dependent kinase (CDK) inhibitor, with IC₅₀s of 5-25 nM for CDK1, CDK2, CDK3, CDK4, CDK7 and CDK9.

HY-128587

Mevociclib

Inhibitor 99.27%

Mevociclib (SY-1365) is a potent and first-in-class selective CDK7 inhibitor, with a K_i of 17.4 nM.

HY-10012

AZD-5438

Inhibitor 99.85%

AZD-5438 is a potent CDK1, CDK2, and CDK9 inhibitor, with IC₅₀s of 16 nM, 6 nM, and 20 nM in cell-free assays, respectively.

HY-103248

Toyocamycin

Inhibitor 99.90%

Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor.

HY-103712A

Samuraciclib hydrochloride

Inhibitor 99.98%

Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC₅₀ of 41 nM.

HY-10424

Milciclib

Inhibitor 99.89%

Milciclib (PHA-848125) is a potent, ATP-competitive and dual inhibitor of CDK and Tropomyosin receptor kinase (TRK), with IC₅₀s of 45, 150, 160, 363, 398 nM and 53 nM for cyclin A/CDK2, cyclin H/CDK7, cyclin D1/CDK4, cyclin E/CDK2, cyclin B/CDK1 and TRKA, respectively.

HY-11009

CGP60474

Inhibitor 99.23%

CGP60474, a highly potent anti-endotoxemic agent, is a potent cyclin-dependent kinase (CDK) inhibitor (IC₅₀ values are 26, 3, 4, 216, 10, 200 and 13 nM for CDK1/B, CDK2/E, CDK2/A, CDK4/D, CDK5/p25, CDK7/H and CDK9/T, respectively).

HY-101257B

YKL-5-124 TFA

Inhibitor 99.44%

YKL-5-124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC₅₀s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively.

HY-10014

R547

Inhibitor 99.57%

R547 is a potent, selective and orally active ATP-competitive CDK inhibitor, with K_is of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively.

[email protected]

609-228-6898

Find Your Local Distributor

MedChemExpress
Contact Us
About Us
Headquarters
Distributors
Statement on False Report
Careers
Customer Support
Technical Support
Service
Ordering Information
Easy Return
Shipping Rates & Policies
Intellectual Property Promise
Resources
Free Sample
Resources
Molarity Calculator
Dilution Calculator
Terms & Conditions
Reconstitution Calculator
Specific Activity Calculator

Subscribe to our E-newsletter

Name

Email *

Sorry, but the email address you supplied was invalid.

Thanks, your subscription has been confirmed. You will hear from us soon.

Submission failed, please try again later.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2023 MedChemExpress. All Rights Reserved.

Site Map Privacy Policy

Join with us

As the situation with COVID-19 continues to unfold in every community, MedChemExpress is responding to the uncertainty caused by this outbreak thoughtfully and cautiously. Your need for high quality reagent doesn't stop during difficult times, and neither do we. We're doing our best to keep everyone healthy and safe in the workplace while also avoiding the interruptions to our day-to-day operations. If you need to change the delivery plan for items ordered, please contact us via email [email protected]. Thank you for being a loyal MedChemExpress customer, we are here to assist you as needed.