1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-155004
    SDH-IN-3
    SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 7.2 μg/mL. SDH-IN-3 exhibits excellent antifungal activities against Nigrospora oryzae with an EC50 of 1.9 μg/mL. SDH-IN-3 can be used for anti-infection research.
    SDH-IN-3
  • HY-126559
    Ansatrienin A
    Ansatrienin A is an antifungal antibiotic that can be isolated from Streptomyces collinus.
    Ansatrienin A
  • HY-105519
    M 14659
    M 14659 is a potent injectable semisynthetic cephalosporin antibiotic. M 14659 has a strong inhibitory effect on Gram-negative bacteria, including Pseudomonas aeruginosa.
    M 14659
  • HY-131107
    Cefpodoxime proxetil impurity B
    Cefpodoxime proxetil impurity B is an impurity of Cefpodoxime proxetil (HY-N7101). Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin.
    Cefpodoxime proxetil impurity B
  • HY-131554
    Tibezonium iodide
    Tibezonium iodide, an oropharyngeal disinfectant, has antibacterial activity for the prevention of mouth infections.
    Tibezonium iodide
  • HY-113427AS
    cis-Vaccenic acid-d13
    cis-Vaccenic acid-d13 is the deuterium labeled cis-Vaccenic acid. cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate, acts a potential fetal hemoglobin inducer.
    cis-Vaccenic acid-d<sub>13</sub>
  • HY-183935
    NDM-1-IN-13
    Activator
    NDM-1-IN-13 is a NDM-1 inhibitor with an IC50 of 3.27 μM. As an Antibiotic synergist, NDM-1-IN-13 synergistically reduces the minimum inhibitory concentration of Meropenem (HY-13678) against NDM-1-positive bacterial isolates. NDM-1-IN-13 can be used in studies related to NDM-1-positive bacterial infections.
    NDM-1-IN-13
  • HY-N6687B
    Calcimycin hemimagnesium
    Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis and autophagy.
    Calcimycin hemimagnesium
  • HY-B0220B
    Erythromycin (gluceptate)
    Erythromycin gluceptate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin gluceptate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin gluceptate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
    Erythromycin (gluceptate)
  • HY-119002
    BO-1236
    BO-1236 is a compound with antibacterial activity. It has strong activity against Gram-negative bacteria including Pseudomonas aeruginosa. It has shown activity superior to or equivalent to that of some commonly used antibiotics in in vitro and in vivo experiments, and has a certain stability against β-lactamase.
    BO-1236
  • HY-N14959
    Deacetylravidomycin N-oxide
    Deacetylravidomycin N-oxide is an antibiotic that can be produced by Streptomyces ravidus S50905. Deacetylravidomycin N-oxide is active against Gram-positive bacteria but inactive against Gram-negative bacteria. Deacetylravidomycin N-oxide has antitumor activity against P388 leukemia and methamphetamine A fibrosarcoma.
    Deacetylravidomycin N-oxide
  • HY-N11056
    Justicidin C
    Justicidin C is an antiviral lignan. Justicidin C shows strong antiviral activity against vesicular stomatitis virus and low cytotoxicity against rabbit lung cells (RL-33).
    Justicidin C
  • HY-P10603
    SP1
    SP1 is an α-peptide encoded by the mating pheromone MFα1 gene in Candida albicans, which can induce cell growth arrest at the mating type locus MTLa in Candida albicans. SP1 can be used in the study of the prevention and treatment of Candida albicans infection.
    SP1
  • HY-125092
    Drimentine C
    Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine β lymphocyte myeloma cells by 63 and 98% in vitro when used at concentrations of 12.5 and 100 μg/mL, respectively.
    Drimentine C
  • HY-113627A
    Undecylprodigiosin hydrochloride
    Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities.
    Undecylprodigiosin hydrochloride
  • HY-147331A
    Oseltamivir acid methyl ester hydrochloride
    Oseltamivir acid methyl ester hydrochloride is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester hydrochloride is converted to oseltamivir acid by carboxylesterase 1 (CES1).
    Oseltamivir acid methyl ester hydrochloride
  • HY-N15263
    Cepafungin III
    Cepafungin III is an acylpeptide antibiotic that can be isolated from the culture broth of Pseudomonas species. Cepafungin III exhibits inhibitory activity against yeast and fungi, and antitumor activity against P388 leukemia in mice, when mixed with Cepafungin I and II.
    Cepafungin III
  • HY-113595
    Temafloxacin hydrochloride
    Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections.
    Temafloxacin hydrochloride
  • HY-146328R
    PqsR/LasR-IN-2 (Standard)
    PqsR/LasR-IN-2 (Standard) is the analytical standard of PqsR/LasR-IN-2. This product is intended for research and analytical applications. PqsR/LasR-IN-2 (Compound 3) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-2 also inhibits hERG with the IC50 of 1.408 µM[1].
    PqsR/LasR-IN-2 (Standard)
  • HY-100528R
    Nanchangmycin (Standard)
    Nanchangmycin (Standard) is the analytical standard of Nanchangmycin. This product is intended for research and analytical applications. Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria[1]. Nanchangmycin is a broad spectrum antiviral active against Zika virus[2].
    Nanchangmycin (Standard)

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