Nanchangmycin (Standard)
Nanchangmycin (Standard) is the analytical standard of Nanchangmycin. This product is intended for research and analytical applications. Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria[1]. Nanchangmycin is a broad spectrum antiviral active against Zika virus[2].
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- CAS No.: 65101-87-3
- 화학식: C47H77NaO14
- 분자량:889.10
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Antibiotic Isoforms
More
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| JEG-3 | CC50 |
6.1 μM
Compound: 1
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Cytotoxicity against human JEG3 cells incubated for 36 hrs by resazurin-dye based Alamar blue assay
Cytotoxicity against human JEG3 cells incubated for 36 hrs by resazurin-dye based Alamar blue assay
|
[PMID: 31549836] |
Chemical Information
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CAS No. 65101-87-3
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분자량 889.10
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화학식 C47H77NaO14
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SMILES
C[C@H]1[C@@]2(O[C@]([C@@]3([H])O[C@](O)([C@H](C)C[C@@H]3C)CO)([H])C[C@@H]2C)O[C@]([C@]4(O[C@]5(O[C@]([C@H](C)[C@@H](O)C5)([H])[C@@H](C)/C=C(C)/C([C@H](C)C[C@H](C)C(O[Na])=O)=O)CC4)C)([H])C[C@@H]1O[C@@]6([H])O[C@@H]([C@@H](OC)CC6)C
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Synonyms
Nanchangmycin A (Standard)
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Liu T et al. Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic nanchangmycin. Chem Biol. 2008 May;15(5):449-58. [Content Brief]
[2]. Rausch K, et al. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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