1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-130837R
    JH-LPH-28 (Standard)
    JH-LPH-28 (Standard) is the analytical standard of JH-LPH-28. This product is intended for research and analytical applications. JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL[1].
    JH-LPH-28 (Standard)
  • HY-B0756
    Cefazolin sodium pentahydrate
    Cefazolin sodium pentahydrate is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin sodium pentahydrate has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
    Cefazolin sodium pentahydrate
  • HY-W012941R
    2-Thiophenecarboxaldehyde (Standard)
    2-Thiophenecarboxaldehyde (Standard) is the analytical standard of 2-Thiophenecarboxaldehyde. This product is intended for research and analytical applications. 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities.
    2-Thiophenecarboxaldehyde (Standard)
  • HY-182326
    WF-3161
    WF-3161 (FR900261) is a cyclic tetrapeptide antibiotic isolated from the fungus Petriella guttulata with anti-tumor activity. WF-3161 inhibits the growth of Trichophyton asteroides with an MIC of 3 μg/mL. WF-3161 is applicable to research related to P-388 leukemia.
    WF-3161
  • HY-126406
    Tirandamycin A
    Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.
    Tirandamycin A
  • HY-N10174
    Tomaymycin
    Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria.
    Tomaymycin
  • HY-P5468
    NRC-16
    NRC-16 is a biological active peptide. (pleurocidin-like cationic AMP)
    NRC-16
  • HY-P5746
    Suicin 65
    Suicin 65 is a class I type B lantibiotic produced by Streptococcus suis. Suicin 65 is active against all S. suis isolates.
    Suicin 65
  • HY-130069
    Teicoplanin A2-5
    Teicoplanin A2-5 is an antibiotic active against Gram-positive aerobic and anaerobic bacteria.
    Teicoplanin A2-5
  • HY-W704402
    Glyceryl 1-monooctanoate-d5
    Glyceryl 1-monooctanoate-d5 is the deuterium labeled Glyceryl 1-monooctanoate (HY-W012444). Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria.
    Glyceryl 1-monooctanoate-d<sub>5</sub>
  • HY-135531
    Cefuzonam
    Cefuzonam is an antibiotic, which exhibits antibacterial activity against gram positive bacteria, such as Staphylococcus, Streptococcus and Neisseria gonorrhoeae, with MIC ranginf from 0.63 to 2 μg/mL. Cefuzonam is an inhibitor for mild steel corrosion by increasing hydrophobicity of the metal surface to the acid solution .
    Cefuzonam
  • HY-N8381
    Berkeleylactone E
    Berkeleylactone E is a macrolide antibiotic.
    Berkeleylactone E
  • HY-106911
    Sanfetrinem cilexetil
    Sanfetrinem cilexetil (GV 118819X), a prodrug of Sanfetrinem (HY-106922), is an orally active antibiotic. Sanfetrinem cilexetil shows potent efficacy against experimental murine septicemia caused by Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli and against murine respiratory infections caused by Streptococcus pneumoniae.
    Sanfetrinem cilexetil
  • HY-125656
    Bostrycin
    Bostrycin (Rhodosporin) is a new type of red pigment antibiotic that is primarily effective against Gram-positive bacteria.
    Bostrycin
  • HY-105284R
    Sulopenem (Standard)
    N-Acetylneuraminic acid (Standard) is the analytical standard of N-Acetylneuraminic acid. This product is intended for research and analytical applications. N-Acetylneuraminic acid (NANA; Lactaminic acid), a nonphenolic structure, is the predominant form of sialic from Collocalia esculenta. N-Acetylneuraminic acid plays a biological role in myocardial injury, melanoma and viral or bacterial infection. N-Acetylneuraminic acid inhibits melanogenesis by reducing tyrosinase activity and triggers myocardial injury in vitro and in vivo by activation of the Rho/Rho-associated signaling pathway through binding to RhoA and Cdc42. N-Acetylneuraminic acid may prevent high fat diet (HFD)-induced inflammation and oxidative stress, thereby prevents hyperlipidemia-associated inflammation and oxidative stress. N-Acetylneuraminic acid is promising for research in the field of melanoma, coronary artery, obesity-related diseases and hyperlipidemia.
    Sulopenem (Standard)
  • HY-105841A
    Tetronasin sodium
    Tetronasin (M 139603) sodium is a growth-promoting antibiotic with activity against Gram-­positive bacteria. Tetronasin sodium is an oral activity that can be administered in the animal's food or water supply.
    Tetronasin sodium
  • HY-W738281
    Chlorhexidine-d8
    Chlorhexidine-d8 is deuterium-labeled Chlorhexidine (HY-B1248). Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
    Chlorhexidine-d<sub>8</sub>
  • HY-N5161
    Arborcandin B
    Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida.
    Arborcandin B
  • HY-N8295
    Leucomycin A13
    Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 μg/mL, respectively. It binds to ribosomes with an IC50 value of 1.2 μM in a radioligand binding assay.
    Leucomycin A13
  • HY-W338859
    Levofloxacin mesylate
    Levofloxacin mesylate is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin mesylate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin mesylate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin mesylate shows anti-orthopoxvirus activity.
    Levofloxacin mesylate

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