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Tomaymycin

Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria.

For research use only. We do not sell to patients.

CAS No.: 35050-55-6
Formula: C₁₆H₂₀N₂O₄
Molecular Weight:304.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Tomaymycin Chemical Structure

CAS No.: 35050-55-6

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Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria^[1]^[2].

IC₅₀ & Target

Antibiotic^[1]^[2]

All Antibiotic Isoforms :

In Vivo

Tomaymycin, an antiphage antibiotic is produced by cultivation of Streptomyces achromogenes var. tomaymyceticus in a lactose-bouillon medium enriched with yeast extract and phosphate salts. The antiphage activity is strong against Escherichia coli T1, T3 phages and Bacillus subtilis M-2, SP-10 phages. The LD₅₀ (i.p.) of tomaymycin for mice is estimated at 3.0 mg/kg.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 35050-55-6
Molecular Weight 304.34
Formula C₁₆H₂₀N₂O₄
SMILES

O=C1N2[C@](C/C(C2)=C\C)([H])[C@H](NC3=CC(O)=C(OC)C=C31)OC
Structure Classification
- Phenols
- Monophenols
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces achromogenes
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. F L Boyd, et al. Characterization of a unique tomaymycin-d(CICGAATTCICG)2 adduct containing two drug molecules per duplex by NMR, fluorescence, and molecular modeling studies. Biochemistry. 1990 Mar 6;29(9):2387-403. [Content Brief]

[2]. K Arima, et al. Studies on tomaymycin, a new antibiotic. I. Isolation and properties of tomaymycin. J Antibiot (Tokyo). 1972 Aug;25(8):437-44. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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