35050-55-6
35050-55-6
Chemical Structure
Tomaymycin
- CAS No.: 35050-55-6
- Formula:C16H20N2O4
- Molecular Weight:304.34
IUPAC Name: (11R,11aS,E)-2-ethylidene-8-hydroxy-7,11-dimethoxy-1,2,3,10,11,11a-hexahydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one
InChIKey: UQVNRKBFAXNOGA-LWTNMJDUSA-N
SMILES: O=C1N2[C@](C/C(C2)=C\C)([H])[C@H](NC3=CC(O)=C(OC)C=C31)OC
Biological Activity: Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria[1][2].
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Tomaymycin | Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria. | |||||||||||||||||||||
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References
- [1]. F L Boyd, et al. Characterization of a unique tomaymycin-d(CICGAATTCICG)2 adduct containing two drug molecules per duplex by NMR, fluorescence, and molecular modeling studies. Biochemistry. 1990 Mar 6;29(9):2387-403. [Content Brief]
- [2]. K Arima, et al. Studies on tomaymycin, a new antibiotic. I. Isolation and properties of tomaymycin. J Antibiot (Tokyo). 1972 Aug;25(8):437-44. [Content Brief]
Keywords
