1. Anti-infection
    Cell Cycle/DNA Damage
  2. Bacterial
    DNA/RNA Synthesis
    Parasite
    Antibiotic
  3. Tirandamycin A

Tirandamycin A 

Cat. No.: HY-126406
Handling Instructions

Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.

For research use only. We do not sell to patients.

Tirandamycin A Chemical Structure

Tirandamycin A Chemical Structure

CAS No. : 34429-70-4

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Description

Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties[1][2].

In Vitro

A 60 μM treatment with Tirandamycin A results in a slightly stronger inhibition, demonstrating a 84.2% reduction in growth of Entamoeba histolytica HM-1:IMSS and 64.8% reduction in growth by Entamoeba histolytica Col. Tirandamycin A inhibits chain initiation and elongation of bacterial RNA polymerase without acting on mammalian polymerases[1].

Molecular Weight

417.45

Formula

C₂₂H₂₇NO₇

CAS No.

34429-70-4

SMILES

O=C(/C1=C(O)\C=C\C(C)=C\[[email protected]]([[email protected]@H]2[[email protected]@H](C)[[email protected]@]3([H])C([[email protected]]4([H])O[[email protected]]4(C)[[email protected]@](O3)(C)O2)=O)C)NCC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Tirandamycin ABacterialDNA/RNA SynthesisParasiteAntibioticanti-amoebicantimicrobialantibacterialInhibitorinhibitorinhibit

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Tirandamycin A
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