34429-70-4
34429-70-4
Chemical Structure
Tirandamycin A
- CAS No.: 34429-70-4
- Formula:C22H27NO7
- Molecular Weight:417.45
IUPAC Name: (E)-3-((R,2E,4E)-1-hydroxy-4-methyl-6-((1S,2S,4R,6S,7R,8R)-1,2,7-trimethyl-5-oxo-3,9,10-trioxatricyclo[4.3.1.02,4]decan-8-yl)hepta-2,4-dien-1-ylidene)pyrrolidine-2,4-dione
InChIKey: URGUBECARCAPRI-UYWODMNRSA-N
SMILES: O=C(/C1=C(O)\C=C\C(C)=C\[C@H]([C@@H]2[C@@H](C)[C@@]3([H])C([C@]4([H])O[C@]4(C)[C@@](O3)(C)O2)=O)C)NCC1=O
Biological Activity: Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties[1][2].
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Tirandamycin A | Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties. | |||||||||||||||||||||
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References
- [1]. Avelina Espinosa, et al. Antiamoebic properties of the actinomycete metabolites echinomycin A and tirandamycin A. Parasitol Res. 2012 Dec;111(6):2473-7. [Content Brief]
- [2]. H Hagenmaier, et al. Metabiolic products of microorganisms. Tirandamycin B(author's transl). Arch Microbiol. 1976 Aug;109(1-2):65-74. [Content Brief]
Keywords
