2. Anti-infection Autophagy Others
  3. Bacterial Antibiotic Autophagy Isotope-Labeled Compounds
  4. Azithromycin-d3

Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

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Azithromycin-d<sub>3</sub>

Azithromycin-d3 Estructura química

No. CAS : 163921-65-1

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5 mg En stock
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50 mg   Obtener un presupuesto  

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Based on 1 Customer Validation

Other Forms of Azithromycin-d3:

Azithromycin-d3 Related Antibodies

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

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Descripciòn

Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

IC50 & Target

Macrolide

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Azithromycin-d3 Related Antibodies
Peso molecular

752.00

Fòrmula

C38H69D3N2O12
No. CAS
Unlabeled CAS
Appearance

Solid

Color

White to light yellow

SMILES

C[C@H]([C@@H](O[C@@]([H])([C@@H]1O)O[C@@H](C[C@@H]1N(C)C)C)[C@](C[C@@H](C)CN2C([2H])([2H])[2H])(C)O)[C@H](O[C@@]([H])(C[C@]3(OC)C)O[C@H]([C@@H]3O)C)[C@@H](C)C(O[C@@H]([C@@](O)([C@@H]([C@H]2C)O)C)CC)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

Ethanol : ≥ 100 mg/mL (132.98 mM)

DMSO : 100 mg/mL (132.98 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3298 mL 6.6489 mL 13.2979 mL
5 mM 0.2660 mL 1.3298 mL 2.6596 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.7%

SDS (252 KB)

COA (267 KB) Elemental Analysis Report (123 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO 1 mM 1.3298 mL 6.6489 mL 13.2979 mL 33.2447 mL
5 mM 0.2660 mL 1.3298 mL 2.6596 mL 6.6489 mL
10 mM 0.1330 mL 0.6649 mL 1.3298 mL 3.3245 mL
15 mM 0.0887 mL 0.4433 mL 0.8865 mL 2.2163 mL
20 mM 0.0665 mL 0.3324 mL 0.6649 mL 1.6622 mL
25 mM 0.0532 mL 0.2660 mL 0.5319 mL 1.3298 mL
30 mM 0.0443 mL 0.2216 mL 0.4433 mL 1.1082 mL
40 mM 0.0332 mL 0.1662 mL 0.3324 mL 0.8311 mL
50 mM 0.0266 mL 0.1330 mL 0.2660 mL 0.6649 mL
60 mM 0.0222 mL 0.1108 mL 0.2216 mL 0.5541 mL
80 mM 0.0166 mL 0.0831 mL 0.1662 mL 0.4156 mL
100 mM 0.0133 mL 0.0665 mL 0.1330 mL 0.3324 mL
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Azithromycin-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azithromycin-d3163921-65-1BacterialAntibioticAutophagyIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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Nombre del producto:
Azithromycin-d3
Cat. No.:
HY-17506S
Cantidad:
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SAFETY DATA SHEET (SDS)

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