1. GPCR/G Protein Neuronal Signaling
  2. mAChR
  3. Cycrimine

Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder.

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Cycrimine

Cycrimine 構造式

CAS 番号 : 77-39-4

容量 価格(税別) 在庫状況 数量
1 mg $160 在庫あり
5 mg $380 在庫あり
10 mg $600 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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製品説明

Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder[1][2][3][4].

分子量

287.44

分子式

C19H29NO

CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

OC(C1CCCC1)(C2=CC=CC=C2)CCN3CCCCC3

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

溶剤 & 溶解度
体外: 

DMSO : 25 mg/mL (86.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4790 mL 17.3949 mL 34.7899 mL
5 mM 0.6958 mL 3.4790 mL 6.9580 mL
10 mM 0.3479 mL 1.7395 mL 3.4790 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

×
体積 (終了)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.85%

参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4790 mL 17.3949 mL 34.7899 mL 86.9747 mL
5 mM 0.6958 mL 3.4790 mL 6.9580 mL 17.3949 mL
10 mM 0.3479 mL 1.7395 mL 3.4790 mL 8.6975 mL
15 mM 0.2319 mL 1.1597 mL 2.3193 mL 5.7983 mL
20 mM 0.1739 mL 0.8697 mL 1.7395 mL 4.3487 mL
25 mM 0.1392 mL 0.6958 mL 1.3916 mL 3.4790 mL
30 mM 0.1160 mL 0.5798 mL 1.1597 mL 2.8992 mL
40 mM 0.0870 mL 0.4349 mL 0.8697 mL 2.1744 mL
50 mM 0.0696 mL 0.3479 mL 0.6958 mL 1.7395 mL
60 mM 0.0580 mL 0.2899 mL 0.5798 mL 1.4496 mL
80 mM 0.0435 mL 0.2174 mL 0.4349 mL 1.0872 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
Cycrimine
製品番号:
HY-119918
数量:
MCE 日本正規代理店: