77-39-4
77-39-4
Chemical Structure
Cycrimine
- CAS No.: 77-39-4
- Formula:C19H29NO
- Molecular Weight:287.44
IUPAC Name: 1-cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
InChIKey: SWRUZBWLEWHWRI-UHFFFAOYSA-N
SMILES: OC(C1CCCC1)(C2=CC=CC=C2)CCN3CCCCC3
Biological Activity: Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder[1][2][3][4].
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Cycrimine | 99.85% | Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder. | ||||||||||||||||||||
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References
- [1]. David T. CHAU. Methods of treating behaviorial and/or mental disorders. WO2014176460A1.
- [2]. Marzoughi S, et al. Tardive neurotoxicity of anticholinergic drugs: A review. J Neurochem. 2021 Sep;158(6):1334-1344. [Content Brief]
- [3]. Tacke, et al. Syntheses and pharmacological characterization of achiral and chiral enantiopure C/Si/Ge-analogous derivatives of the muscarinic antagonist cycrimine: a study on C/Si/Ge bioisosterism. Journal of organometallic chemistry 640.1-2 (2001): 140-
- [4]. MAGEE KR, et al. Antispasmodic compound 08958 in treatment of paralysis agitans. J Am Med Assoc. 1953 Oct 24;153(8):715-8. [Content Brief]
Keywords
