Cycrimine
Based on 1 Customer Validation
Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder.
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- Purity : 99.85%
- CAS No.: 77-39-4
- 화학식: C19H29NO
- 분자량:287.44
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보관:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 77-39-4
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Appearance Solid
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분자량 287.44
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화학식 C19H29NO
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Color White to off-white
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SMILES
OC(C1CCCC1)(C2=CC=CC=C2)CCN3CCCCC3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
용액&용해도
In Vitro:
DMSO : 25 mg/mL (86.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. David T. CHAU. Methods of treating behaviorial and/or mental disorders. WO2014176460A1.
[2]. Marzoughi S, et al. Tardive neurotoxicity of anticholinergic drugs: A review. J Neurochem. 2021 Sep;158(6):1334-1344. [Content Brief]
[4]. MAGEE KR, et al. Antispasmodic compound 08958 in treatment of paralysis agitans. J Am Med Assoc. 1953 Oct 24;153(8):715-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4790 mL | 17.3949 mL | 34.7899 mL | 86.9747 mL |
| 5 mM | 0.6958 mL | 3.4790 mL | 6.9580 mL | 17.3949 mL | |
| 10 mM | 0.3479 mL | 1.7395 mL | 3.4790 mL | 8.6975 mL | |
| 15 mM | 0.2319 mL | 1.1597 mL | 2.3193 mL | 5.7983 mL | |
| 20 mM | 0.1739 mL | 0.8697 mL | 1.7395 mL | 4.3487 mL | |
| 25 mM | 0.1392 mL | 0.6958 mL | 1.3916 mL | 3.4790 mL | |
| 30 mM | 0.1160 mL | 0.5798 mL | 1.1597 mL | 2.8992 mL | |
| 40 mM | 0.0870 mL | 0.4349 mL | 0.8697 mL | 2.1744 mL | |
| 50 mM | 0.0696 mL | 0.3479 mL | 0.6958 mL | 1.7395 mL | |
| 60 mM | 0.0580 mL | 0.2899 mL | 0.5798 mL | 1.4496 mL | |
| 80 mM | 0.0435 mL | 0.2174 mL | 0.4349 mL | 1.0872 mL |
Cycrimine Related Classifications
HY-119918 Related Classifications
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