Gly-7-MAD-MDCPT hydrochloride

Cat. No.: HY-132164A Purity: 98.27%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Gly-7-MAD-MDCPT (Compound 4b) hydrochloride is an anticancer agent. Gly-7-MAD-MDCPT hydrochloride is a Camptothecin (HY-16560) compound, which shows cytotoxicity to various cancer cells with IC₅₀ values of 10-1000 nM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Gly-7-MAD-MDCPT hydrochloride 화학구조

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	견적 받기	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Gly-7-MAD-MDCPT hydrochloride:

Gly-7-MAD-MDCPT 견적 받기

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All ADC Payload Isoform Specific Products:

View All Isoforms

Auristatin Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

View All Topoisomerase Isoform Specific Products:

View All Isoforms

Topoisomerase Topo I Topo II DNA gyrase

Biological Activity
순도&문서
References
고객리뷰

제품 설명

분자량

514.92

화학식

C₂₄H₂₃ClN₄O₇

Appearance

Solid

Color

Light yellow to yellow

SMILES

NCC(NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.Cl

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

DMSO : 16.67 mg/mL (32.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9420 mL	9.7102 mL	19.4205 mL
5 mM	0.3884 mL	1.9420 mL	3.8841 mL
10 mM	0.1942 mL	0.9710 mL	1.9420 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.27%

Select Batch:

Data Sheet (276 KB) SDS (251 KB)

COA (261 KB) HNMR (530 KB) CNMR (105 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9420 mL	9.7102 mL	19.4205 mL	48.5512 mL
	5 mM	0.3884 mL	1.9420 mL	3.8841 mL	9.7102 mL
	10 mM	0.1942 mL	0.9710 mL	1.9420 mL	4.8551 mL
	15 mM	0.1295 mL	0.6473 mL	1.2947 mL	3.2367 mL
	20 mM	0.0971 mL	0.4855 mL	0.9710 mL	2.4276 mL
	25 mM	0.0777 mL	0.3884 mL	0.7768 mL	1.9420 mL
	30 mM	0.0647 mL	0.3237 mL	0.6473 mL	1.6184 mL