Search Result
Results for "
gly-phe-
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-148668
-
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SHR-A1811 Drug-linker
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM) .
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- HY-W011063
-
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Cathepsin
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Metabolic Disease
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Gly-Phe-β-naphthylamide is a substrate of Cathepsin C (HY-P2922) and belongs to the lysosomal agonist. Gly-Phe-β-naphthylamide can freely pass through the cell membrane and organelle membrane. Gly-Phe-β-naphthylamide will be specifically hydrolyzed by Cathepsin C, ultimately leading to a permeability lysis when it enters the acidic compartment. Gly-Phe-β-naphthylamide can be used to study lysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C .
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- HY-147164
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate .
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- HY-44246
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Mc-GGFG-OH
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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- HY-131990
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-44235
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
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- HY-P3669
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ADC Linker
Drug Intermediate
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Cancer
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Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689) .
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- HY-131833
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-P1449
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ADC Linker
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Cancer
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Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
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-
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- HY-P0073
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Met-Enkephalin; Methionine enkephalin; Metenkefalin
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Opioid Receptor
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Neurological Disease
Cancer
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Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
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-
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- HY-45672
-
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ADC Linker
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Cancer
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
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- HY-P4192
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ADC Linker
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Cancer
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Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
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-
- HY-13631M
-
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Drug-Linker Conjugates for ADC
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Cancer
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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis.
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- HY-177442
-
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DS-3939
|
Antibody-Drug Conjugates (ADCs)
Mucin
Topoisomerase
Apoptosis
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Cancer
|
|
DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .
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- HY-136432
-
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Mc-GGFG-PAB-OH
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ADC Linker
|
Cancer
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Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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- HY-45545
-
-
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- HY-13631F
-
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research .
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- HY-W090940
-
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ADC Linker
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Cancer
|
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H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.
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- HY-W013998
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-
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- HY-153795
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a bioactive drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC). Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is applicable to ADC synthesis and cancer research. Exatecan acts as a DNA Topoisomerase I inhibitor .
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- HY-49412
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Drug Intermediate
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Others
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Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives .
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- HY-P4425
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Biochemical Assay Reagents
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Others
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Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases .
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- HY-W090942
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Endogenous Metabolite
Sodium Channel
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Others
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Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis .
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- HY-164762
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SHR-A1811
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Antibody-Drug Conjugates (ADCs)
EGFR
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Cancer
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Trastuzumab rezetecan (SHR-A1811) is a HER2-targeting antibody-drug conjugate (ADC). Trastuzumab rezetecan is composed of a humanized anti-HER2 antibody (HY-P9907), a cleavable linker MC-Gly-Gly-Phe-Gly (HY-44246), and a topoisomerase I inhibitor payload Rezetecán (HY-147408). Trastuzumab rezetecan can be used for research in HER2-positive breast cancer .
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- HY-148668A
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-
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- HY-147307
-
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a agent-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer .
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- HY-W014000
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- HY-132134
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Biochemical Assay Reagents
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Cancer
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MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research .
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- HY-150402
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-
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- HY-153067
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan (Compound 11) is a bioactive compound-linker conjugate for ADC. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan can conjugate with antibodies to form ADC (C-11) with anti-tumor activity. Exatecan is a DNA Topoisomerase I inhibitor. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan can be used in the research of squamous cell carcinoma, pancreatic adenocarcinoma and colorectal cancer .
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- HY-P3558
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-
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- HY-160649
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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MC-Gly-Gly-Phe-Gly-GABA-Exatecan is an agent linker conjugate for ADC, with an inhibitor for Topoisomerase Exatecan (HY-13631) with IC50 of 22 μM. MC-Gly-Gly-Phe-Gly-GABA-Exatecan targets various antibodies, exhibits cytotoxic and antitumor efficacy in vitro and in vivo .
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- HY-45669
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PROTAC Linkers
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Cancer
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Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
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- HY-131833A
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).
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- HY-49057
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Gly-cyclopropylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-P3555
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- HY-P1449A
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ADC Linker
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Cancer
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Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
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- HY-136432A
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Mc-GGFG-PAB-OH TFA
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ADC Linker
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Cancer
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Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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- HY-400258
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-OSu is an ADC linker. MC-Gly-Gly-Phe-OSu can be used for the research of cancer .
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- HY-131833G
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-177711
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SHR-A1921
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Antibody-Drug Conjugates (ADCs)
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Cancer
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Tizetatug rezetecan (SHR-A1921) is an Antibody-drug Conjugate (ADC) composed of antibody Tizetatug (HY-P991032) and MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (HY-148668). Tizetatug rezetecan can be used for the research of cancer .
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- HY-164829
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Drug-Linker Conjugates for ADC
Microtubule/Tubulin
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Cancer
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Mal-C5-Gly-Gly-Phe-MMAE (Compound S5) is a drug-linker conjugate for ADC. Mal-C5-Gly-Gly-Phe-MMAE consists of MMAE (HY-15162) and a linker. Mal-C5-Gly-Gly-Phe-MMAE can be used for synthesis of ADCs and for cancer research .
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- HY-148812
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- HY-131990G
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-178146
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ADC Linker
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Cancer
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Mc-Lys(PEG12)-Cap-Ala-Ala-PABC is a linker of MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (HY-178146) .
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- HY-148773
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Boc is involved in the synthesis of antibody-drug conjugates (ADCs) to Trastuzumab (HY-P9907). MC-Gly-Gly-Phe-Boc can participate in cancer research .
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- HY-137186
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Proteasome
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Others
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Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM .
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- HY-44234
-
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-178290
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Drug-Linker Conjugates for ADC
Drug Intermediate
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Cancer
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MC-Gly-Gly-Phe-Exatecan analog 38 (Compound L-II-4) is part of an antibody-drug conjugate (ADC), consisting of an ADC toxicant molecule and an ADC linker. MC-Gly-Gly-Phe-Exatecan analog 38 can be used to synthesize ADCs (such as ADC-II-15 and ADC-III-13). MC-Gly-Gly-Phe-Exatecan analog 38 can also be used in cancer research (ADC Cytotoxin: HY-178315, ADC Linker: HY-44235) .
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-
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- HY-P2651
-
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Fluorescent Dye
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Others
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Dansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP .
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- HY-P3555A
-
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Opioid Receptor
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Others
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D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist .
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- HY-45672G
-
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ADC Linker
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Cancer
|
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
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- HY-160453
-
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Drug-Linker Conjugates for ADC
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Others
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH is a camptothecin derivative. MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH can be used for antibody drug conjugate (ADC) .
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- HY-131990S
-
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- HY-160683
-
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Drug-Linker Conjugates for ADC
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Cancer
|
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin (Compound 7) can be used as a linker-drug intermediate for the synthesis of antibody-drug conjugates (ADCs) .
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- HY-P4334
-
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Bz-Arg-gly-phe-phe-Leu-4MβNA
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Fluorescent Dye
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Others
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Bz-RGFFL-4MβNA (Bz-Arg-Gly-Phe-Phe-Leu-4MβNA) is a peptide and can be used fluorogenic substrate .
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- HY-49463
-
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ADC Linker
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Neurological Disease
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Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Gly-CH2-O-CH2-Cbz is an ADC linker that can be used in the synthesis of ADCs (such as Trastuzumab deruxtecan and U3-1402).
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- HY-W013998S
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-
- HY-44234A
-
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-D-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OtBu is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu (HY-44234) .
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- HY-181429
-
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Drug-Linker Conjugates for ADC
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Cancer
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Fmoc-Gly-Gly-Phe-Gly-Paclitaxel (Compound 16a-3) is a drug-linker conjugates for ADC. Fmoc-Gly-Gly-Phe-Gly-Paclitaxel contains the ADC linker Fmoc-Gly-Gly-Phe-OH (HY-131833) and a potent tubulin polymerization inhibitor Paclitaxel (HY-B0015). Fmoc-Gly-Gly-Phe-Gly-Paclitaxel can be used for the research of cancer .
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- HY-W298929
-
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Biochemical Assay Reagents
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Others
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Fmoc-Gly-Phe-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-183681S1
-
-
- HY-181428
-
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Drug-Linker Conjugates for ADC
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Cancer
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Fmoc-Gly-Gly-Phe-Gly-Docetaxel (compound 16h-3) is a drug-linker conjugate for ADC, which comprises a microtubule depolymerization inhibitor and a linker. Puxitatug samrotecan drug-linker can be used to synthesize antibody-drug conjugate (ADC) .
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- HY-178279
-
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Drug-Linker Conjugates for ADC
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Others
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Mc-Gly-Gly-Phe-Gly-PAB-pSar11-Exatecan (compound L-D-5) is a toxin-linker compound that can be used for the preparation of antibody-drug conjugates (ADCs) .
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- HY-183254
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- HY-185460
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Antibody-Drug Conjugates (ADCs)
EGFR
PI3K
mTOR
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Cancer
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Pertuzumab-LD3 is a humanized antibody-drug conjugate (ADC) targeting HER2. Pertuzumab-LD3 consists of the anti-HER2 humanized IgG1 monoclonal antibody Pertuzumab (HY-P9912), the cleavable linker Gly-Gly-Phe-Gly (HY-P3669), and the PI3K/mTOR-IN-21 (HY-185456) payload. Pertuzumab-LD3 can be used in research on metastatic HER2-positive breast cancer.
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| Cat. No. |
Product Name |
Type |
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- HY-177442
-
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DS-3939
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Fluorescent Dye
|
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DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .
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- HY-164762
-
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SHR-A1811
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Fluorescent Dye
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Trastuzumab rezetecan (SHR-A1811) is a HER2-targeting antibody-drug conjugate (ADC). Trastuzumab rezetecan is composed of a humanized anti-HER2 antibody (HY-P9907), a cleavable linker MC-Gly-Gly-Phe-Gly (HY-44246), and a topoisomerase I inhibitor payload Rezetecán (HY-147408). Trastuzumab rezetecan can be used for research in HER2-positive breast cancer .
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- HY-131833G
-
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Fluorescent Dye
|
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Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-131990G
-
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Fluorescent Dye
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-45672G
-
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Fluorescent Dye
|
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
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- HY-160453
-
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Fluorescent Dye
|
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH is a camptothecin derivative. MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH can be used for antibody drug conjugate (ADC) .
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| Cat. No. |
Product Name |
Type |
-
- HY-131833G
-
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Biochemical Assay Reagents
|
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Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-131990G
-
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Biochemical Assay Reagents
|
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-45672G
-
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Biochemical Assay Reagents
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P3669
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ADC Linker
Drug Intermediate
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Cancer
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Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689) .
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- HY-P1449
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ADC Linker
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Cancer
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Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
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- HY-P0073
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Met-Enkephalin; Methionine enkephalin; Metenkefalin
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Opioid Receptor
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Neurological Disease
Cancer
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Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
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-
- HY-P4192
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ADC Linker
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Cancer
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Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
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-
- HY-136432
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Mc-GGFG-PAB-OH
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ADC Linker
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Cancer
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Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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- HY-W013998
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- HY-P4425
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Biochemical Assay Reagents
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Others
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Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases .
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-
- HY-W014000
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-
- HY-P3558
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-
- HY-P3555
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-
- HY-P1449A
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ADC Linker
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Cancer
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Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
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- HY-136432A
-
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Mc-GGFG-PAB-OH TFA
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ADC Linker
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Cancer
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Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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-
- HY-P0296
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Peptides
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Others
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Gly-Phe-Arg is a superpotent synthetic tripeptide mimics of the mud-crab pumping pheromone.
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-
- HY-P4251
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-
- HY-137186
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|
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Proteasome
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Others
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Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM .
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-
- HY-P3559
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Peptides
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Others
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Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu is a β-lipotropin peptide. Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu is a polypeptide of 8 amino acids .
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- HY-P2651
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Fluorescent Dye
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Others
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Dansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP .
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-
- HY-P5094
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Peptides
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Others
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FA-Gly-Phe-Leu is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P3555A
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Opioid Receptor
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Others
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D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist .
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-
- HY-P4334
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|
Bz-Arg-gly-phe-phe-Leu-4MβNA
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Fluorescent Dye
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Others
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Bz-RGFFL-4MβNA (Bz-Arg-Gly-Phe-Phe-Leu-4MβNA) is a peptide and can be used fluorogenic substrate .
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- HY-W013998S
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-131990S
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5 is deuterated labeled MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH .
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-
-
- HY-W013998S
-
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Glycyl-L-phenylalanine-d2 is a deuterium labeled Glycyl-L-phenylalanine (HY-W013998). Glycyl-L-phenylalanine is a phenylalanine derivative.
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-
- HY-183681S1
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Mal-C6-Gly-Phe-Cpg-7-MAD-MDCPT-d2 is the deuterium labeled Mal-C6-Gly-Phe-Cpg-7-MAD-MDCPT.
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-
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-131833G
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-131990G
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ADC Linker
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Cancer
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
-
- HY-45672G
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ADC Linker
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Cancer
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
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-
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