Z-Gly-Gly-Phe-OH
Based on 1 Customer Validation
Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis.
For research use only. We do not sell to patients.
- Purity: 99.46%
- CAS No.: 13171-93-2
- Formula: C21H23N3O6
- Molecular Weight:413.42
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Z-Gly-Gly-Phe-OH (25 mM; 80 min) reacts with 50 mM H-Leu-NHPh in ethylene glycol-acetate buffer to generate Z-Gly-Gly-Phe-Leu-NHPh in a pepsin-catalyzed peptide bond synthesis experiment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 13171-93-2
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Appearance Solid
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Molecular Weight 413.42
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Formula C21H23N3O6
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Color White to light yellow
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SMILES
O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(OCC2=CC=CC=C2)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (241.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4188 mL | 12.0942 mL | 24.1885 mL | 60.4712 mL |
| 5 mM | 0.4838 mL | 2.4188 mL | 4.8377 mL | 12.0942 mL | |
| 10 mM | 0.2419 mL | 1.2094 mL | 2.4188 mL | 6.0471 mL | |
| 15 mM | 0.1613 mL | 0.8063 mL | 1.6126 mL | 4.0314 mL | |
| 20 mM | 0.1209 mL | 0.6047 mL | 1.2094 mL | 3.0236 mL | |
| 25 mM | 0.0968 mL | 0.4838 mL | 0.9675 mL | 2.4188 mL | |
| 30 mM | 0.0806 mL | 0.4031 mL | 0.8063 mL | 2.0157 mL | |
| 40 mM | 0.0605 mL | 0.3024 mL | 0.6047 mL | 1.5118 mL | |
| 50 mM | 0.0484 mL | 0.2419 mL | 0.4838 mL | 1.2094 mL | |
| 60 mM | 0.0403 mL | 0.2016 mL | 0.4031 mL | 1.0079 mL | |
| 80 mM | 0.0302 mL | 0.1512 mL | 0.3024 mL | 0.7559 mL | |
| 100 mM | 0.0242 mL | 0.1209 mL | 0.2419 mL | 0.6047 mL |
Z-Gly-Gly-Phe-OH Related Classifications
HY-W090942 Related Classifications
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