Mal-C5-Gly-Gly-Phe-MMAE
Mal-C5-Gly-Gly-Phe-MMAE (Compound S5) is a drug-linker conjugate for ADC. Mal-C5-Gly-Gly-Phe-MMAE consists of MMAE (HY-15162) and a linker. Mal-C5-Gly-Gly-Phe-MMAE can be used for synthesis of ADCs and for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3056230-14-6
- Formula: C68H104N10O14
- Molecular Weight:1285.61
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 3056230-14-6
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Appearance Solid
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Molecular Weight 1285.61
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Formula C68H104N10O14
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C([C@H](CC(C)C)NC([C@@H](NC(CNC(CNC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (77.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.7778 mL | 3.8892 mL | 7.7784 mL | 19.4460 mL |
| 5 mM | 0.1556 mL | 0.7778 mL | 1.5557 mL | 3.8892 mL | |
| 10 mM | 0.0778 mL | 0.3889 mL | 0.7778 mL | 1.9446 mL | |
| 15 mM | 0.0519 mL | 0.2593 mL | 0.5186 mL | 1.2964 mL | |
| 20 mM | 0.0389 mL | 0.1945 mL | 0.3889 mL | 0.9723 mL | |
| 25 mM | 0.0311 mL | 0.1556 mL | 0.3111 mL | 0.7778 mL | |
| 30 mM | 0.0259 mL | 0.1296 mL | 0.2593 mL | 0.6482 mL | |
| 40 mM | 0.0194 mL | 0.0972 mL | 0.1945 mL | 0.4862 mL | |
| 50 mM | 0.0156 mL | 0.0778 mL | 0.1556 mL | 0.3889 mL | |
| 60 mM | 0.0130 mL | 0.0648 mL | 0.1296 mL | 0.3241 mL |
Mal-C5-Gly-Gly-Phe-MMAE Related Classifications
HY-164829 Related Classifications
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