2. Cell Cycle/DNA Damage Antibody-drug Conjugate/ADC Related
  3. Topoisomerase Drug-Linker Conjugates for ADC
  4. MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan 

Cat. No.: HY-148668A Purity: 95.11%
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MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM).

For research use only. We do not sell to patients.

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Chemical Structure

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Chemical Structure

CAS No. : 2414254-52-5

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Based on 1 publication(s) in Google Scholar

Other Forms of MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan:

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Related Antibodies

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Description

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

IC50 & Target[1]

Topoisomerase I

 

Molecular Weight

1074.12

Formula

C55H60FN9O13
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C3CC3)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan2414254-52-5TopoisomeraseDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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