2414254-52-5

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Chemical Structure
2414254-52-5

Chemical Structure

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

  • CAS No.: 2414254-52-5
  • Formula:C55H60FN9O13
  • Molecular Weight:1074.12

IUPAC Name: (1s,3s)-3-(2-(4-(8-chloro-4-oxo-4H-chromen-2-yl)phenoxy)ethoxy)cyclobutane-1-carboxylic acid

InChIKey: WKCCHLIWLNJSMH-DVXRIDOZSA-N

SMILES: O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C3CC3)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O

Biological Activity: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

Cat. No. Product Name Purity Description Pricing
HY-148668A
MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan 98.99% MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM).
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References