Boc-Gly-Gly-Phe-Gly-OH TFA
Based on 1 Customer Validation
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
For research use only. We do not sell to patients.
- Purity : 98.27%
- CAS No.: 2450273-39-7
- Formula: C22H29F3N4O9
- Molecular Weight:550.48
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2450273-39-7
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Appearance Solid
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Molecular Weight 550.48
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Formula C22H29F3N4O9
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Color White to off-white
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Sequence Shortening
Boc-GGFG
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 125 mg/mL (227.07 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.8166 mL | 9.0830 mL | 18.1660 mL | 45.4149 mL |
| 5 mM | 0.3633 mL | 1.8166 mL | 3.6332 mL | 9.0830 mL | |
| 10 mM | 0.1817 mL | 0.9083 mL | 1.8166 mL | 4.5415 mL | |
| 15 mM | 0.1211 mL | 0.6055 mL | 1.2111 mL | 3.0277 mL | |
| 20 mM | 0.0908 mL | 0.4541 mL | 0.9083 mL | 2.2707 mL | |
| 25 mM | 0.0727 mL | 0.3633 mL | 0.7266 mL | 1.8166 mL | |
| 30 mM | 0.0606 mL | 0.3028 mL | 0.6055 mL | 1.5138 mL | |
| 40 mM | 0.0454 mL | 0.2271 mL | 0.4541 mL | 1.1354 mL | |
| 50 mM | 0.0363 mL | 0.1817 mL | 0.3633 mL | 0.9083 mL | |
| 60 mM | 0.0303 mL | 0.1514 mL | 0.3028 mL | 0.7569 mL | |
| 80 mM | 0.0227 mL | 0.1135 mL | 0.2271 mL | 0.5677 mL | |
| 100 mM | 0.0182 mL | 0.0908 mL | 0.1817 mL | 0.4541 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Boc-Gly-Gly-Phe-Gly-OH TFA Related Classifications
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