Boc-Gly-Gly-Phe-Gly-OH TFA

Name: Boc-Gly-Gly-Phe-Gly-OH TFA
Brand: MedChemExpress
SKU: HY-P1449A
Rating: 4.5 (1 reviews)

Cat. No.: HY-P1449A Purity: 98.27%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Boc-Gly-Gly-Phe-Gly-OH TFA Chemical Structure

CAS No. : 2450273-39-7

Size	Price	Stock	Quantity
5 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Boc-Gly-Gly-Phe-Gly-OH TFA:

Boc-Gly-Gly-Phe-Gly-OH In-stock

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View All Isoforms

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Biological Activity
Purity & Documentation
Customer Review

Description

Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

IC₅₀ & Target

Cleavable Linker

Molecular Weight

550.48

Formula

C₂₂H₂₉F₃N₄O₉

CAS No.

2450273-39-7

Appearance

Solid

Color

White to off-white

Sequence Shortening

Boc-GGFG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (227.07 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8166 mL	9.0830 mL	18.1660 mL
5 mM	0.3633 mL	1.8166 mL	3.6332 mL
10 mM	0.1817 mL	0.9083 mL	1.8166 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.27%

Select Batch:

Data Sheet (245 KB) SDS (252 KB)

COA (251 KB) HNMR (205 KB) LCMS (123 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.8166 mL	9.0830 mL	18.1660 mL	45.4149 mL
	5 mM	0.3633 mL	1.8166 mL	3.6332 mL	9.0830 mL
	10 mM	0.1817 mL	0.9083 mL	1.8166 mL	4.5415 mL
	15 mM	0.1211 mL	0.6055 mL	1.2111 mL	3.0277 mL
	20 mM	0.0908 mL	0.4541 mL	0.9083 mL	2.2707 mL
	25 mM	0.0727 mL	0.3633 mL	0.7266 mL	1.8166 mL
	30 mM	0.0606 mL	0.3028 mL	0.6055 mL	1.5138 mL
	40 mM	0.0454 mL	0.2271 mL	0.4541 mL	1.1354 mL
	50 mM	0.0363 mL	0.1817 mL	0.3633 mL	0.9083 mL
	60 mM	0.0303 mL	0.1514 mL	0.3028 mL	0.7569 mL
	80 mM	0.0227 mL	0.1135 mL	0.2271 mL	0.5677 mL
	100 mM	0.0182 mL	0.0908 mL	0.1817 mL	0.4541 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.