Magnesium isoglycyrrhizinate hydrate

Cat. No.: HY-154795 Purity: 99.81%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant (Glycyrrhiza glabra). Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats.

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Magnesium isoglycyrrhizinate hydrate 화학구조

CAS No. : 658701-67-8

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	견적 받기
50 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of Magnesium isoglycyrrhizinate hydrate:

18α-Glycyrrhizic acid In-stock

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Caspase Isoform Specific Products:

View All Isoforms

Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

View All NOD-like Receptor (NLR) Isoform Specific Products:

View All Isoforms

NLRP3 NLRP1 NOD1 NOD2

Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

Caspase-1

분자량

917.28

화학식

C₄₂H₆₈MgO₂₀

CAS No.

658701-67-8

Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@]3([H])C[C@](C)(CC4)C(O)=O)C)C)=O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C([O-])=O)O)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C([O-])=O)C)([H])CC1)C.[Mg+2].O.O.O.O

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 33.33 mg/mL (36.34 mM; adjust pH to 9 with NH3·H2O)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0902 mL	5.4509 mL	10.9018 mL
5 mM	0.2180 mL	1.0902 mL	2.1804 mL
10 mM	0.1090 mL	0.5451 mL	1.0902 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.81%

Select Batch:

Data Sheet (281 KB) SDS (252 KB)

COA (264 KB) HNMR (309 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Yang Y, et al., Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease. BMC Pulm Med. 2021 Nov 15;21(1):371. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.0902 mL	5.4509 mL	10.9018 mL	27.2545 mL
	5 mM	0.2180 mL	1.0902 mL	2.1804 mL	5.4509 mL
	10 mM	0.1090 mL	0.5451 mL	1.0902 mL	2.7254 mL
	15 mM	0.0727 mL	0.3634 mL	0.7268 mL	1.8170 mL
	20 mM	0.0545 mL	0.2725 mL	0.5451 mL	1.3627 mL
	25 mM	0.0436 mL	0.2180 mL	0.4361 mL	1.0902 mL
	30 mM	0.0363 mL	0.1817 mL	0.3634 mL	0.9085 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.