Magnesium isoglycyrrhizinate hydrate

製品番号: HY-154795 純度: 99.81%: Data Sheet SDS COA 取扱説明書
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Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant (Glycyrrhiza glabra). Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Magnesium isoglycyrrhizinate hydrate 構造式

CAS 番号 : 658701-67-8

容量	価格（税別）	在庫状況	数量
5 mg	$75	在庫あり	Estimated Time of Arrival: December 31
10 mg		お問い合わせ
50 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Other Forms of Magnesium isoglycyrrhizinate hydrate:

18α-Glycyrrhizic acid 在庫あり

Caspase アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

NOD-like Receptor (NLR) アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

NLRP3 NLRP1 NOD1 NOD2

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target

Caspase-1

分子量

917.28

分子式

C₄₂H₆₈MgO₂₀

CAS 番号

658701-67-8

Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@]3([H])C[C@](C)(CC4)C(O)=O)C)C)=O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C([O-])=O)O)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C([O-])=O)C)([H])CC1)C.[Mg+2].O.O.O.O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度

体外:

H₂O : 33.33 mg/mL (36.34 mM; adjust pH to 9 with NH3·H2O)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0902 mL	5.4509 mL	10.9018 mL
5 mM	0.2180 mL	1.0902 mL	2.1804 mL
10 mM	0.1090 mL	0.5451 mL	1.0902 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.81%

Select Batch:

データシート (281 KB) SDS (252 KB)

COA (264 KB) HNMR (309 KB) LCMS (94 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Yang Y, et al., Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease. BMC Pulm Med. 2021 Nov 15;21(1):371. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.0902 mL	5.4509 mL	10.9018 mL	27.2545 mL
	5 mM	0.2180 mL	1.0902 mL	2.1804 mL	5.4509 mL
	10 mM	0.1090 mL	0.5451 mL	1.0902 mL	2.7254 mL
	15 mM	0.0727 mL	0.3634 mL	0.7268 mL	1.8170 mL
	20 mM	0.0545 mL	0.2725 mL	0.5451 mL	1.3627 mL
	25 mM	0.0436 mL	0.2180 mL	0.4361 mL	1.0902 mL
	30 mM	0.0363 mL	0.1817 mL	0.3634 mL	0.9085 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.