2. PROTAC Epigenetics Cell Cycle/DNA Damage
  3. Ligands for Target Protein for PROTAC HDAC
  4. POI ligand 1

POI ligand 1 is a template for the non-selective HDAC inhibitor Vorinostat (HY-10221). POI ligand 1 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC HDAC degraders with antitumor activity. POI ligand 1 can be used for the synthesis of FF2049 (HY-168863).

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POI ligand 1

POI ligand 1 Chemische Struktur

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POI ligand 1 Related Antibodies

Top Publications Citing Use of Products

Alle HDAC Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Beschreibung

POI ligand 1 is a template for the non-selective HDAC inhibitor Vorinostat (HY-10221). POI ligand 1 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC HDAC degraders with antitumor activity. POI ligand 1 can be used for the synthesis of FF2049 (HY-168863)[1].

Molekulargewicht

279.33

Formel

C14H21N3O3
SMILES

ONC(CCCCCCNC(C1=CC=C(C=C1)N)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
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POI ligand 1 Related Classifications

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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

POI ligand 1POI ligand1POI ligand-1Ligands for Target Protein for PROTACHDACTarget Protein-binding MoietyHistone deacetylasesMM.1SMV4?11MDA-MB-231AntiproliferativeTPD.Inhibitorinhibitorinhibit

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