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  3. Drug Intermediate Cytochrome P450
  4. (R)-4-Benzyl-2-oxazolidinone

(R)-4-Benzyl-2-oxazolidinone  (Synonyms: (R)-4-ベンジル-2-オキサゾリジノン)

製品番号: HY-W007664 純度: 99.73%
COA 取扱説明書 Technical Support

(R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. (R)-4-Benzyl-2-oxazolidinone is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, (R)-4-Benzyl-2-oxazolidinone not only serves as a key precursor for the synthesis of aromatase inhibitors, but also can be used in studies related to estrogen-dependent breast cancer.

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(R)-4-Benzyl-2-oxazolidinone

(R)-4-Benzyl-2-oxazolidinone 構造式

CAS 番号 : 102029-44-7

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 29 在庫あり
Solution
10 mM * 1 mL in DMSO USD 29 在庫あり
Solid
10 g $27 在庫あり
25 g $55 在庫あり
50 g $82 在庫あり
100 g $124 在庫あり
250 g $248 在庫あり
500 g $373 在庫あり
1000 g $560 在庫あり
> 100 g   お問い合わせ  

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(R)-4-Benzyl-2-oxazolidinone 関連抗体

Top Publications Citing Use of Products

Cytochrome P450 アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

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製品説明

(R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. (R)-4-Benzyl-2-oxazolidinone is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, (R)-4-Benzyl-2-oxazolidinone not only serves as a key precursor for the synthesis of aromatase inhibitors, but also can be used in studies related to estrogen-dependent breast cancer[1][2].

IC50 & Target

Aromatase

 

体外実験

4-Benzyl-2-oxazolidinone serves as the core chiral parent nucleus of aromatase inhibitors, and the inhibitory activity of derivatives of (R)-4-Benzyl-2-oxazolidinone is significantly superior to that of (S)-4-Benzyl-2-oxazolidinone[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(R)-4-Benzyl-2-oxazolidinone 関連抗体
分子量

177.20

分子式

C10H11NO2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC1)N[C@@H]1CC2=CC=CC=C2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 50 mg/mL (282.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6433 mL 28.2167 mL 56.4334 mL
5 mM 1.1287 mL 5.6433 mL 11.2867 mL
10 mM 0.5643 mL 2.8217 mL 5.6433 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.83%

COA (249 KB) HNMR (132 KB) LCMS (322 KB) GC (211 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.6433 mL 28.2167 mL 56.4334 mL 141.0835 mL
5 mM 1.1287 mL 5.6433 mL 11.2867 mL 28.2167 mL
10 mM 0.5643 mL 2.8217 mL 5.6433 mL 14.1084 mL
15 mM 0.3762 mL 1.8811 mL 3.7622 mL 9.4056 mL
20 mM 0.2822 mL 1.4108 mL 2.8217 mL 7.0542 mL
25 mM 0.2257 mL 1.1287 mL 2.2573 mL 5.6433 mL
30 mM 0.1881 mL 0.9406 mL 1.8811 mL 4.7028 mL
40 mM 0.1411 mL 0.7054 mL 1.4108 mL 3.5271 mL
50 mM 0.1129 mL 0.5643 mL 1.1287 mL 2.8217 mL
60 mM 0.0941 mL 0.4703 mL 0.9406 mL 2.3514 mL
80 mM 0.0705 mL 0.3527 mL 0.7054 mL 1.7635 mL
100 mM 0.0564 mL 0.2822 mL 0.5643 mL 1.4108 mL
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(R)-4-Benzyl-2-oxazolidinone Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-4-Benzyl-2-oxazolidinone102029-44-7Drug IntermediateCytochrome P450Drug IintermediateCYPschiral auxiliarynatural productsaromatase inhibitorsestrogen-dependent breast cancerpharmaceutical agentsEvans' chiral oxazolidinone(R)-phenylalaninolstereoselective asymmetric alkylation reactionsInhibitorinhibitorinhibit

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製品名:
(R)-4-Benzyl-2-oxazolidinone
製品番号:
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