102029-44-7
Chemical Structure
(R)-4-Benzyl-2-oxazolidinone
- CAS No.: 102029-44-7
- Formula:C10H11NO2
- Molecular Weight:177.20
IUPAC Name: (R)-4-benzyloxazolidin-2-one
InChIKey: OJOFMLDBXPDXLQ-SECBINFHSA-N
SMILES: O=C(OC1)N[C@@H]1CC2=CC=CC=C2
Biological Activity: (R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. (R)-4-Benzyl-2-oxazolidinone is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, (R)-4-Benzyl-2-oxazolidinone not only serves as a key precursor for the synthesis of aromatase inhibitors, but also can be used in studies related to estrogen-dependent breast cancer[1][2].
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(R)-4-Benzyl-2-oxazolidinone | 99.73% | (R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. (R)-4-Benzyl-2-oxazolidinone is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, (R)-4-Benzyl-2-oxazolidinone not only serves as a key precursor for the synthesis of aromatase inhibitors, but also can be used in studies related to estrogen-dependent breast cancer. | ||||||||||||||||||||
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- [1]. Ahmed S, et al. Novel oxazolidinone based compounds as inhibitors of aromatase and the use of the substrate-heme complex approach in the rationalisation of these compounds. Biochem Biophys Res Commun. 2002;294(2):380-383. [Content Brief]
- [2]. Heravi M M, e tal. Applications of oxazolidinones as chiral auxiliaries in the asymmetric alkylation reaction applied to total synthesis[J]. RSC advances, 2016, 6(36): 30498-30551.
Keywords
